Results 241 to 250 of about 27,648,855 (348)

National, regional and provincial prevalence of peripheral artery disease in Chinese adults in 2023: an updated systematic review and modelling study. [PDF]

J Glob Health
Zhou J, Shan S, Shen G, Tan B, Ying J, Rudan I, Song P, Global Health Epidemiology Research Group (GHERG).   +7 more
europepmc   +1 more source

Modelling considerations [PDF]

, 2010
Blackford, S.C., Gehlen, M., Oschlies, Andreas   +2 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Geospatial approaches for mapping zero-dose children in low- and lower-1 middle-income countries: A scoping review

Njogu AM, Musau MM, Srivastava S, Menegale F, Clarke E, Mudereri C, Kitema FR, Opanga Y, Mmbando A, Gashaija A, Sibomana H, Condo J, Osei F, Benova L, Blanford JI, Poletti P, Torbica A, Melegaro A, Federici C, Macharia PM.   +19 more
europepmc   +1 more source

Highly Efficient Deep Learning-Enabled Parameterization and 3D Reconstruction of Traditional Chinese Roof Structures. [PDF]

Sensors (Basel)
Ou R, Yang F, Li L, Cheng L, Qian L, He Y, Che M, Zhang C.   +7 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Bayesian hierarchical modelling of academic orientation and advising effects on student retention and progression: Multi-cohort evidence. [PDF]

PLoS One
Mosia M, Sekonyela L, Egara FO, Nimy E, Mabokgole IM, Nannim FA.   +5 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

System dynamics modelling methods for public health policy evaluation: a systematic literature review focussing on mental health and substance use disorders. [PDF]

BMC Public Health
Valkenburg HJ, Ten Dam J, van der Werf S, Feenstra TL, Rodenburg J, Wijnen BFM.   +5 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source