Results 21 to 30 of about 496,267 (268)

Harnessing peak transmission around symptom onset for non-pharmaceutical intervention and containment of the COVID-19 pandemic

open access: yesNature Communications, 2021
Transmission by pre-symptomatic and asymptomatic viral carriers makes intervention and containment of the COVID-19 extremely challenging. Here, the authors construct an epidemiological model that focuses on transmission around the symptom onset ...
Liang Tian   +11 more
doaj   +1 more source

Business Models as Models [PDF]

open access: yesLong Range Planning, 2010
Drawing on research undertaken in the history and philosophy of science, with particular reference to the extensive literature which discusses the use of models in biology and economics, we explore the question ‘Are Business Models useful?’ We point out that they act as various forms of model: to provide means to describe and classify businesses; to ...
Baden-Fuller, C., Morgan, M.S.
openaire   +3 more sources

Insights from quantitative and mathematical modelling on the proposed WHO 2030 goal for schistosomiasis [version 1; peer review: 2 approved, 1 approved with reservations]

open access: yesGates Open Research, 2019
Schistosomiasis remains one of the neglected tropical diseases (NTDs) impacting millions of people around the world. The World Health Organization (WHO) recently proposed a goal of elimination as a public health problem (EPHP) for schistosomiasis to be ...
NTD Modelling Consortium Schistosomiasis Group
doaj   +1 more source

Concept and application of the probability of pharmacological success (PoPS) as a decision tool in drug development: a position paper

open access: yesJournal of Translational Medicine, 2023
Background In drug development, few molecules from a large pool of early candidates become successful medicines after demonstrating a favourable benefit-risk ratio.
Chao Chen   +4 more
doaj   +1 more source

Insights from mathematical modelling and quantitative analysis on the proposed WHO 2030 targets for visceral leishmaniasis on the Indian subcontinent [version 1; peer review: 2 approved]

open access: yesGates Open Research, 2019
Visceral leishmaniasis (VL) is a neglected tropical disease (NTD) caused by Leishmania protozoa that are transmitted by female sand flies. On the Indian subcontinent (ISC), VL is targeted by the World Health Organization (WHO) for elimination as a public
NTD Modelling Consortium Visceral Leishmaniasis Group
doaj   +1 more source

Frequent and unpredictable changes in COVID-19 policies and restrictions reduce the accuracy of model forecasts

open access: yesScientific Reports, 2023
Between June and August 2020, an agent-based model was used to project rates of COVID-19 infection incidence and cases diagnosed as positive from 15 September to 31 October 2020 for 72 geographic settings.
Farah Houdroge   +11 more
doaj   +1 more source

Protocol for the production of micro- and nanoplastic test materials

open access: yesMicroplastics and Nanoplastics, 2023
Micro- and nanoplastics (MNP) are ubiquitous, but little is known about the risks they pose to human health. Currently available data are of limited use for developing relevant risk assessments due to poor quality control, the lack of a standardised ...
Luke A. Parker   +8 more
doaj   +1 more source

Modeling Model Uncertainty [PDF]

open access: yesJournal of the European Economic Association, 2002
Recently there has been a great deal of interest in studying monetary policy under model uncertainty. We develop new methods to analyze different sources of uncertainty in one coherent structure, which is useful for policy decisions. We show how to estimate the size of the uncertainty based on time series data, and how to incorporate this uncertainty ...
Onatski, Alexei, Williams, Noah
openaire   +5 more sources

Insights from quantitative analysis and mathematical modelling on the proposed WHO 2030 goals for soil-transmitted helminths [version 2; peer review: 2 approved]

open access: yesGates Open Research, 2019
Soil-transmitted helminths (STHs) are a group of parasitic worms that infect humans, causing a wide spectrum of disease, notably anaemia, growth retardation, and delayed cognitive development.
NTD Modelling Consortium discussion group on soil-transmitted helminths
doaj   +1 more source

The influence of Holmium substitution on the magnetic and mechanical properties of Nd2Fe14B: a first principle study [PDF]

open access: yesMATEC Web of Conferences, 2023
In this study, the ab initio density functional theory (DFT) approach is used to investigate the effect of Holmium (Ho) on the magnetic and mechanical properties of Nd2Fe14B magnets.
Baloyi Mphamela Enos   +2 more
doaj   +1 more source

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