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Modeling Model Slicers [PDF]

open access: yes, 2011
Among model comprehension tools, model slicers are tools that extract a subset from a model, for a specific purpose. Model slicers are tools that let modelers rapidly gather relevant knowledge from large models. However, existing slicers are dedicated to one modeling language. This is an issue when we observe that new domain specific modeling languages
Blouin, Arnaud   +3 more
openaire   +2 more sources

Insights from quantitative and mathematical modelling on the proposed WHO 2030 goal for schistosomiasis [version 2; peer review: 2 approved, 1 approved with reservations]

open access: yesGates Open Research, 2019
Schistosomiasis remains one of the neglected tropical diseases (NTDs) impacting millions of people around the world. The World Health Organization (WHO) recently proposed a goal of elimination as a public health problem (EPHP) for schistosomiasis to be ...
NTD Modelling Consortium Schistosomiasis Group
doaj   +1 more source

Insights from quantitative and mathematical modelling on the proposed WHO 2030 goals for Chagas disease [version 1; peer review: 2 approved]

open access: yesGates Open Research, 2019
Chagas disease (CD) persists as one of the neglected tropical diseases (NTDs) with a particularly large impact in the Americas. The World Health Organization (WHO) recently proposed goals for CD elimination as a public health problem to be reached by ...
Collaborating Group on Chagas Disease Modelling
doaj   +1 more source

The roadmap towards elimination of lymphatic filariasis by 2030: insights from quantitative and mathematical modelling [version 1; peer review: 2 approved]

open access: yesGates Open Research, 2019
The Global Programme to Eliminate Lymphatic Filariasis was launched in 2000 to eliminate lymphatic filariasis (LF) as a public health problem by 1) interrupting transmission through mass drug administration (MDA) and 2) offering basic care to those ...
NTD Modelling Consortium Lymphatic Filariasis Group
doaj   +1 more source

Harnessing peak transmission around symptom onset for non-pharmaceutical intervention and containment of the COVID-19 pandemic

open access: yesNature Communications, 2021
Transmission by pre-symptomatic and asymptomatic viral carriers makes intervention and containment of the COVID-19 extremely challenging. Here, the authors construct an epidemiological model that focuses on transmission around the symptom onset ...
Liang Tian   +11 more
doaj   +1 more source

Insights from quantitative and mathematical modelling on the proposed WHO 2030 goal for schistosomiasis [version 1; peer review: 2 approved, 1 approved with reservations]

open access: yesGates Open Research, 2019
Schistosomiasis remains one of the neglected tropical diseases (NTDs) impacting millions of people around the world. The World Health Organization (WHO) recently proposed a goal of elimination as a public health problem (EPHP) for schistosomiasis to be ...
NTD Modelling Consortium Schistosomiasis Group
doaj   +1 more source

Concept and application of the probability of pharmacological success (PoPS) as a decision tool in drug development: a position paper

open access: yesJournal of Translational Medicine, 2023
Background In drug development, few molecules from a large pool of early candidates become successful medicines after demonstrating a favourable benefit-risk ratio.
Chao Chen   +4 more
doaj   +1 more source

Conceptual modelling: Towards detecting modelling errors in engineering applications [PDF]

open access: yes, 2019
Rapid advancements of modern technologies put high demands on mathematical modelling of engineering systems. Typically, systems are no longer “simple” objects, but rather coupled systems involving multiphysics phenomena, the modelling of which involves ...
Bird R   +5 more
core   +3 more sources

Modelling ethnogenesis [PDF]

open access: yesBiosystems, 2022
Following the ideas of L.N.Gumilev, we introduce the mathematical model of ethnogenesis which describes the dynamics of subgroups in the developing polity in terms of ordinary differential equations. The bust dynamics associated with the rise and fall of civilisations is modelled as an excitation process, which is the non-linear phenomenon, well known ...
Piunovskiy, Alexey, Vasiev, Bakhtier
openaire   +3 more sources

Insights from mathematical modelling and quantitative analysis on the proposed WHO 2030 targets for visceral leishmaniasis on the Indian subcontinent [version 1; peer review: 2 approved]

open access: yesGates Open Research, 2019
Visceral leishmaniasis (VL) is a neglected tropical disease (NTD) caused by Leishmania protozoa that are transmitted by female sand flies. On the Indian subcontinent (ISC), VL is targeted by the World Health Organization (WHO) for elimination as a public
NTD Modelling Consortium Visceral Leishmaniasis Group
doaj   +1 more source

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