Results 1 to 10 of about 6,631,455 (355)

Modelling and analysing the information processing capabilities of simple biological systems

open access: diamondMathematical Modelling and Analysis, 2012
Biological systems that present basic logic primitives for information processing have already been realized. Models for simulating their dynamics have also been implemented.
Miha Moskon, Miha Mraz
doaj   +3 more sources

The identification of informative genes from multiple datasets with increasing complexity [PDF]

open access: yesBMC Bioinformatics, 2010
Background In microarray data analysis, factors such as data quality, biological variation, and the increasingly multi-layered nature of more complex biological systems complicates the modelling of regulatory networks that can represent and capture the ...
't Hoen Peter AC   +2 more
doaj   +5 more sources

Finding the "dark matter" in human and yeast protein network prediction and modelling. [PDF]

open access: yesPLoS Computational Biology, 2010
Accurate modelling of biological systems requires a deeper and more complete knowledge about the molecular components and their functional associations than we currently have.
Juan A G Ranea   +7 more
doaj   +3 more sources

ECO-BIOLOGICAL SYSTEM MODELING

open access: greenСистемный анализ и прикладная информатика, 2016
The methodology for computer modeling of complex eco-biological models is presented in this paper. It is based on system approach of J. Forrester. Developed methodology is universal for complex ecological and biological systems. Modeling algorithm considers specialties of eco-biological systems and shows adequate and accurate results in practice.
T. I. Burak   +3 more
openalex   +3 more sources

Stochastic biological system-of-systems modelling for iPSC culture

open access: yesCommunications Biology
Large-scale manufacturing of induced pluripotent stem cells (iPSCs) is essential for cell therapies and regenerative medicines. Yet, iPSCs form large cell aggregates in suspension bioreactors, resulting in insufficient nutrient supply and extra metabolic
Hua Zheng   +3 more
doaj   +4 more sources

Modeling adaptive biological systems [PDF]

open access: yesBiosystems, 1989
During the evolution of many systems found in nature, both the system composition and the interactions between components will vary. Equating the dimension with the number of different components, a system which adds or deletes components belongs to a class of dynamical systems with a finite dimensional phase space of variable dimension. We present two
Bagley, R. J.   +5 more
openaire   +3 more sources

Inspecting the Solution Space of Genome-Scale Metabolic Models

open access: yesMetabolites, 2022
Genome-scale metabolic models are frequently used in computational biology. They offer an integrative view on the metabolic network of an organism without the need to know kinetic information in detail.
Seyed Babak Loghmani   +5 more
doaj   +1 more source

Compositional Modeling of Biological Systems [PDF]

open access: green, 2010
Molecular interactions are wired in a fascinating way resulting in complex behavior of bio-logical systems. Theoretical modeling provides us a useful framework for understanding the dynamics and the function of such networks. The complexity of the biological systems calls for conceptual tools that manage the combinatorial explosion of the set of ...
Judit Zámborszky
openalex   +2 more sources

All Driven by Energy Demand? Integrative Comparison of Metabolism of Enterococcus faecalis Wildtype and a Glutamine Synthase Mutant

open access: yesMicrobiology Spectrum, 2022
Lactic acid bacteria (LAB) play a significant role in biotechnology, e.g., food industry and also in human health. Many LAB genera have developed a multidrug resistance in the past few years, causing a serious problem in controlling hospital germs ...
Seyed Babak Loghmani   +11 more
doaj   +1 more source

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