Results 41 to 50 of about 44,204 (260)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A Multiscale Statistical Analysis of Rough Surfaces and Applications to Tribology
MathematicsMathematical modelling of surface roughness is of significant interest for a variety of modern applications, including, but not limited to, tribology and optics. The most popular approaches to modelling rough surfaces are reviewed and critically examined.
Feodor M. Borodich +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Erosion modelling on reconstructed rough surfaces of wind turbine blades
Wind Energy, 2023 Numerical simulations of rain droplet impacts on real rough surfaces of leading edges of wind turbine blades are presented. The effect of rough blade surface conditions during liquid impacts on the stress distribution in the protective coating is studied.
Antonios Tempelis, Leon Mishnaevsky Jr.
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
BRDF-NeRF: Neural radiance fields with optical satellite images and BRDF modelling
International Journal of Applied Earth Observations and GeoinformationNeural radiance fields (NeRF) have gained prominence as a machine learning technique for representing 3D scenes and estimating the bidirectional reflectance distribution function (BRDF) from multiple images. However, most existing research has focused on
Lulin Zhang +4 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
AtmosphereUrban microclimates are traditionally interpreted and modelled based on permanent built surfaces, while semi-permanent elements such as stationary vehicles remain largely overlooked in urban climate studies.
Márcia Matias +5 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source