Results 1 to 10 of about 23,153,291 (313)

Bcl-xL Promotes the Survival of Motor Neurons Derived from Neural Stem Cells

open access: yesBiology, 2023
Neural stem cell (NSC) transplantation creates new hope for the treatment of neurodegenerative disorders by direct differentiation into neurons. However, this technique is limited by poor survival and functional neuron deficiency. In this research study,
Yunqin Wu   +11 more
doaj   +1 more source

Stability of African swine fever virus genome under different environmental conditions [PDF]

open access: yesVeterinary World, 2023
Background and Aim: African swine fever (ASF), a globally transmitted viral disease caused by ASF virus (ASFV), can severely damage the global trade economy.
Wei Zheng   +8 more
doaj   +1 more source

Generation of hiPSCs with ABO c.767T>C substitution: resulting in splicing variants

open access: yesFrontiers in Genetics, 2023
Introduction: The ABO blood group system has important clinical significance in the safety of blood transfusion and organ transplantation. Numerous ABO variations, especially variations in the splice sites, have been identified to be associated with some
Yinge Jin   +12 more
doaj   +1 more source

CRISPR/Cas9 generated knockout mice lacking phenylalanine hydroxylase protein as a novel preclinical model for human phenylketonuria

open access: yesScientific Reports, 2021
Phenylketonuria (PKU) is an autosomal recessive inborn error of l-phenylalanine (Phe) metabolism. It is caused by a partial or complete deficiency of the enzyme phenylalanine hydroxylase (PAH), which is necessary for conversion of Phe to tyrosine (Tyr ...
Kuldeep Singh   +21 more
doaj   +1 more source

Pancreatic and intestinal endocrine cells in zebrafish share common transcriptomic signatures and regulatory programmes

open access: yesBMC Biology, 2020
Background Endocrine cells of the zebrafish digestive system play an important role in regulating metabolism and include pancreatic endocrine cells (PECs) clustered in the islets of Langerhans and the enteroendocrine cells (EECs) scattered in the ...
Arnaud Lavergne   +7 more
doaj   +1 more source

On the forecast skill of a convection-permitting ensemble [PDF]

open access: yesGeoscientific Model Development, 2017
The 2.5 km convection-permitting (CP) ensemble AROME-EPS (Applications of Research to Operations at Mesoscale – Ensemble Prediction System) is evaluated by comparison with the regional 11 km ensemble ALADIN-LAEF (Aire Limitée Adaption dynamique ...
T. Schellander-Gorgas   +5 more
doaj   +1 more source

Journal of Business Models, Vol. 1, No. 1

open access: yesJournal of Business Models, 2013
The Inaugural ...
Journal of Business Models
doaj   +1 more source

New type of microstrip antenna with ferroelectric layer

open access: yesJournal of Telecommunications and Information Technology, 2001
new type of microstrip antenna is proposed using a voltage-controlled ferroelectric thin tape in the multilayered structure. This paper presents the ferroelectric thin tape, its theoretical analysis and design. The results indicate that this concept has
Józef Models, Yevhen Yashchyshyn
doaj   +1 more source

Independent perturbations for physics parametrization tendencies in a convection-permitting ensemble (pSPPT) [PDF]

open access: yesGeoscientific Model Development, 2019
A modification of the widely used SPPT (Stochastically Perturbed Parametrisation Tendencies) scheme is proposed and tested in a Convection-permitting – Limited Area Ensemble Forecasting system (C-LAEF) developed at ZAMG (Zentralanstalt für Meteorologie ...
C. Wastl   +3 more
doaj   +1 more source

Journal of Business Models, Vol. 2, No. 1

open access: yesJournal of Business Models, 2014
Special Issue:  The Business Model Eruption and How Game Changing Mind Sets Challenge Existing Nodes of ...
Journal of Business Models Vol. 2, No. 1
doaj   +1 more source

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