Results 31 to 40 of about 12,044,503 (300)

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider   +15 more
wiley   +1 more source

FGF-induced LHX9 regulates the progression and metastasis of osteosarcoma via FRS2/TGF-β/β-catenin pathway

open access: yesCell Division, 2019
Background Fibroblast growth factor (FGF) and tumor growth factor-β (TGFβ) have emerged as pivotal regulators during the progression of osteosarcoma (OS).
Shuang-Qing Li   +6 more
doaj   +1 more source

Functional interaction between endothelin-1 and ZEB1/YAP signaling regulates cellular plasticity and metastasis in high-grade serous ovarian cancer

open access: yesJournal of Experimental & Clinical Cancer Research, 2022
Background Epithelial-to-mesenchymal transition (EMT) encompasses a highly dynamic and complex key process which leads to metastatic progression. In high-grade serous ovarian carcinoma (HG-SOC), endothelin-1 (ET-1)/endothelin A receptor (ETAR) signaling ...
Rosanna Sestito   +4 more
doaj   +1 more source

Modeling Documents with Event Model [PDF]

open access: yesAlgorithms, 2015
Currently deep learning has made great breakthroughs in visual and speech processing, mainly because it draws lessons from the hierarchical mode that brain deals with images and speech. In the field of NLP, a topic model is one of the important ways for modeling documents. Topic models are built on a generative model that clearly does not match the way
Longhui Wang   +2 more
openaire   +4 more sources

Acute Neurological Events in Children With Hemoglobin SC Disease: A Multicenter Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurological manifestations in children with hemoglobin SC (HbSC) disease remain insufficiently characterized, particularly regarding acute events. The aim of this study was to describe the spectrum and frequency of acute neurological events in a multicenter cohort of children with HbSC disease.
Célia Paulmin   +11 more
wiley   +1 more source

Extracting Domain Models from Textual Requirements in the Era of Large Language Models [PDF]

open access: yes, 2023
Requirements Engineering is a critical part of the software lifecycle, describing what a given piece of software will do (functional) and how it will do it (non-functional).
Mosser, Sébastien   +2 more
core   +1 more source

Mandatory preventive vaccines for infectious diseases expressing T-cell epitopes for cancer prevention

open access: yesInfectious Agents and Cancer
We have previously reported that microorganism-associated antigens (MAAs) share high sequence and conformational homology with tumor-associated antigens (TAAs) as well as T cells cross-react with homologous MAA/TAA pairs.
Concetta Ragone   +7 more
doaj   +1 more source

The Anderson Model as a matrix model [PDF]

open access: yesNuclear Physics B - Proceedings Supplements, 1997
In this paper we describe a strategy to study the Anderson model of an electron in a random potential at weak coupling by a renormalization group analysis. There is an interesting technical analogy between this problem and the theory of random matrices.
Magnen, J., Poirot, G., Rivasseau, V.
openaire   +3 more sources

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan   +3 more
wiley   +1 more source

SARS-CoV-2-specific T cells cross-react with tumor-associated antigens via molecular mimicry

open access: yesJournal of Translational Medicine
Background We have recently described SARS-COV-2 antigens showing sequence and conformational homology to tumor associated antigens (TAAs). Moreover, cross-reactive T cells have been identified in individuals either infected by the SARS-CoV-2 virus or ...
Concetta Ragone   +7 more
doaj   +1 more source

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