Results 51 to 60 of about 17,470,980 (300)

Network Models

Theory and Applications of Categories, 2020
Networks can be combined in various ways, such as overlaying one on top of another or setting two side by side. We introduce "network models" to encode these ways of combining networks. Different network models describe different kinds of networks.
Baez, John C, Foley, John, Moeller, Joe, Pollard, Blake S   +3 more
openaire   +4 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Generation of human induced pluripotent stem cells carrying albumin-sfGFP reporter

Stem Cell Research
Current methodologies for hepatocyte induction from human induced pluripotent stem cells (hiPSCs) have limited efficacy due to lack of a functional hepatocyte reporter.
Jinling Wang, Di Ye, Shuangpeng Li, Xuan Lu, Yue Chi, Chengcheng Tang, Xiaoqing Zhou, Min Chen, Yunwen Zheng, Jianyun Ge, Qingjian Zou   +10 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Shared neoantigens’ atlas for off-the-shelf cancer vaccine development

Journal of Translational Medicine
Background We have recently described that the most prevalent 100 mutations identified in human cancers, both single nucleotide variations (SNVs) and InDels, generate a handful number of shared mutated neoantigens (SNV and InDel-NeoAgs) in association ...
Angela Mauriello, Beatrice Cavalluzzo, Concetta Ragone, Maria Tagliamonte, Luigi Buonaguro   +4 more
doaj   +1 more source

Quo natas, Danio?—Recent Progress in Modeling Cancer in Zebrafish

Frontiers in Oncology, 2017
Over the last decade, zebrafish has proven to be a powerful model in cancer research. Zebrafish form tumors that histologically and genetically resemble human cancers.
Stefanie Kirchberger, Caterina Sturtzel, Susana Pascoal, Martin Distel   +3 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Respuesta inmune sistémica y mucosal contra Neisseria meningitidis B inducida por estrategia de vacunación simultánea mucosal y parental

VacciMonitor, 2009
mmunization is one of the most successful and cost-effective health interventions ever. Immunization have been helping to reduce child mortality, improving maternal health and combating infectious diseases.
González E , Romeu B , del Campo J , Acevedo R, Lastre M, Zayas C, Cuello M, Cabrera O, Balboa J, Nuñez N, Valdez Y, Fariñas M, Pérez O   +12 more
doaj  

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

A novel efficient strategy to generate liver sinusoidal endothelial cells from human pluripotent stem cells

Scientific Reports
Liver sinusoidal endothelial cells (LSECs) are highly specialized endothelial cells (ECs) that play an important role in liver development and regeneration. Additionally, it is involved in various pathological processes, including steatosis, inflammation,
Shang-Ping Tian, Jian-Yun Ge, Yu-Mu Song, Xiao-Qing Yu, Wen-Hao Chen, Yu-Ying Chen, Di Ye, Yun-Wen Zheng   +7 more
doaj   +1 more source