Results 61 to 70 of about 8,909,971 (264)

Practicing Business Model Management in New Ventures

open access: yes, 2017
Purpose: The purpose of this paper is to enhance the knowledge of business modeling in the early phases byexploring its core components and the management of those components.
Johansson, Jeaneth   +5 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

In Proceedings of Workshop on Models versus Exemplars in Computer Vision, CVPR 2001]

open access: yes, 2001
We propose a model- and exemplar-based approach for face recognition. This problem has been previously tackled using either models or exemplars, with limited success.
Combining Models And
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Exploring Models for Pharmacist Prescribing in Ontario

open access: yes, 2015
Two-page overview of what was learned from a citizen panel on the topic of exploring models for pharmacist prescribing in ...
McMaster Health Forum
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Testing for Common Nonlinearities in a Real Tolar - Euro exchange Rate Model

open access: yes, 2006
The common nonlinearity techniques are applied to small models of the real exchange rate, decomposed into its three components, domestic prices, foreign prices, and the nominal exchange ...
Kavkler, Alenka, Böhm, Bernhard
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Panel Summary: Exploring Models for Pharmacist Prescribing in Ontario

open access: yes, 2015
A summary of what was learned from a citizen panel that addressed problems related to pharmacist prescribing, options for addressing these problems, key implementation considerations, and next steps for exploring models for pharmacist prescribing in ...
Ciurea, Ileana   +2 more
core  

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