Results 181 to 190 of about 9,617,821 (263)

Experience-dependent emergence of multi-scale spatial organization during foraging in freely moving marmosets. [PDF]

iScience
El Mahmoudi N, Lanzarini F, Nezhad FZ, Surendran D, Laurens J.   +4 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Correction to "Porcine kidney xenotransplantation: From primate models to clinical reality". [PDF]

Animal Model Exp Med
europepmc   +1 more source

Editorial: Cellular and animal models of neurodegenerative and neuroinflammatory conditions. [PDF]

Front Cell Neurosci
García-León JA, García-Díaz B, Baglietto-Vargas D, Rodriguez-Ortiz CJ.   +3 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A novel mouse calvarial defect model of osteomyelitis induced by Staphylococcus aureus (ATCC 6538). [PDF]

Lab Anim Res
Ko S, Woo HM, Kim K, Kim J.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Experimental Animal Models of Preeclampsia: Mechanisms, Strengths, and Translational Relevance. [PDF]

Arterioscler Thromb Vasc Biol
Reckelhoff JF, Dokic V, Cornelius DC, LaMarca B, Goulopoulou S, Faulkner J, Sones JL, Santillan M, Lin M, Fan JW, Garovic VD.   +10 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Photobiomodulation in animal models of ophthalmic disease: protocol for systematic review and meta-analysis of morphological, visual function, and inflammatory outcomes. [PDF]

Front Med (Lausanne)
Chun JM, Choy S, Seok JW, Kim JD, Park SR.   +4 more
europepmc   +1 more source