Results 231 to 240 of about 3,734,088 (300)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Theory and simulations of delayed stochastic and deterministic models of prion diseases. [PDF]

J Math Biol
Boregowda G, Sharif O, Gutierrez Iii D, Simmons A, Pujo-Menjouet L, Oraby T, Lindstrom MR.   +6 more
europepmc   +1 more source

Selective Induction of Estrogen Receptor-Dependent Stress Signaling as a Therapeutic Strategy in Resistant Breast Cancer. [PDF]

ACS Med Chem Lett
Renner AC, Kargbo RB.
europepmc   +1 more source

Beyond QTL and GWAS: how deep learning, graph models, and multi-omics are reshaping plant genomic prediction analysis. [PDF]

Front Genet
Wang T, Tong R, Yuan Z, Li Y.
europepmc   +1 more source

Quantum biology: From mechanisms to medicine. [PDF]

Clin Transl Med
Sung JY, Cheong JH.
europepmc   +1 more source

Effects of a High-Glucose Diet on Caenorhabditis elegans Key Biological Functions and Survival to Bacterial Infections

ACS Omega
Belisa Avila Rodrigues, Amanda Moreira de Barros, Júlia Machado Menezes, Luisa Jacqueline Maboni, Eduardo Rigon Zimmer, Karine Rigon Zimmer   +5 more
doaj   +1 more source

Twenty-five years of briefings in bioinformatics. [PDF]

Brief Bioinform
Bishop M.
europepmc   +1 more source