Results 31 to 40 of about 3,620,832 (281)

MathSBML: a package for manipulating SBML-based biological models [PDF]

open access: yes, 2004
Summary: MathSBML is a Mathematica package designed for manipulating Systems Biology Markup Language (SBML) models. It converts SBML models into Mathematica data structures and provides a platform for manipulating and evaluating these models.
Doyle, John   +3 more
core   +2 more sources

Involvement of Nrf2-HO-1/JNK-Erk Signaling Pathways in Aconitine-Induced Developmental Toxicity, Oxidative Stress, and ROS-Mitochondrial Apoptosis in Zebrafish Embryos

open access: yesFrontiers in Pharmacology, 2021
Aconitine (AC), one of the bioactive diterpenoid alkaloids extracted from Aconitum plants, is widely used in traditional herbal medicine to treat various diseases.
Qing Xia   +26 more
doaj   +1 more source

Decoding Sequence Classification Models for Acquiring New Biological Insights [PDF]

open access: yes, 2010
Classifying biological sequences is one of the most important tasks in computational biology. In the last decade, support vector machines (SVMs) in combination with sequence kernels have emerged as a de-facto standard.
Andreas Kothmeier   +5 more
core   +2 more sources

Robust Modelling of Biological Neuroregulators [PDF]

open access: yes2005 IEEE Engineering in Medicine and Biology 27th Annual Conference, 2005
The modelling of biological neuroregulated systems is usually complex because of their non-structured and distributed architecture. Software agents are a very useful tool to use in the modelling of this kind of systems, allowing increasing the model with characteristics which are not present in the biological equivalent. This work proposes a model of a
D.R. Fernandez   +5 more
openaire   +4 more sources

BioDiVinE: A Framework for Parallel Analysis of Biological Models [PDF]

open access: yes, 2009
In this paper a novel tool BioDiVinEfor parallel analysis of biological models is presented. The tool allows analysis of biological models specified in terms of a set of chemical reactions. Chemical reactions are transformed into a system of multi-affine
C. Belta   +29 more
core   +2 more sources

At the Biological Modeling and Simulation Frontier [PDF]

open access: yesPharmaceutical Research, 2009
We provide a rationale for and describe examples of synthetic modeling and simulation (M&S) of biological systems. We explain how synthetic methods are distinct from familiar inductive methods. Synthetic M&S is a means to better understand the mechanisms that generate normal and disease-related phenomena observed in research, and how compounds of ...
Hunt, C. Anthony   +6 more
openaire   +4 more sources

Dynamic Influence Networks for Rule-based Models [PDF]

open access: yes, 2017
We introduce the Dynamic Influence Network (DIN), a novel visual analytics technique for representing and analyzing rule-based models of protein-protein interaction networks.
Boutillier, Pierre   +6 more
core   +5 more sources

Duplication Models for Biological Networks [PDF]

open access: yesJournal of Computational Biology, 2003
Are biological networks different from other large complex networks? Both large biological and non-biological networks exhibit power-law graphs (number of nodes with degree k, N(k) ~ k-b) yet the exponents, b, fall into different ranges. This may be because duplication of the information in the genome is a dominant evolutionary force in shaping ...
Chung, Fan   +3 more
openaire   +3 more sources

Boolean Models of Bistable Biological Systems

open access: yes, 2009
This paper presents an algorithm for approximating certain types of dynamical systems given by a system of ordinary delay differential equations by a Boolean network model.
A. Novick   +16 more
core   +1 more source

Interactions between DC-SIGN and the envelope protein from Dengue and Zika viruses: a structural perspective based on molecular dynamics and MM/GBSA analyses

open access: yesVirology Journal, 2023
Zika virus (ZIKV) and dengue virus (DENV) share a lot of similarities being both phylogenetically closely related, share the same insect vector passage for reaching the host, affinity for the same carbohydrate receptor domains (CRDs), indicating feasible
Bruno Stein Barbosa Menechino   +5 more
doaj   +1 more source

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