Results 31 to 40 of about 27,460,944 (326)

Robust Modelling of Biological Neuroregulators [PDF]

open access: yes2005 IEEE Engineering in Medicine and Biology 27th Annual Conference, 2005
The modelling of biological neuroregulated systems is usually complex because of their non-structured and distributed architecture. Software agents are a very useful tool to use in the modelling of this kind of systems, allowing increasing the model with characteristics which are not present in the biological equivalent. This work proposes a model of a
D.R. Fernandez   +5 more
openaire   +4 more sources

Decoding Sequence Classification Models for Acquiring New Biological Insights [PDF]

open access: yes, 2010
Classifying biological sequences is one of the most important tasks in computational biology. In the last decade, support vector machines (SVMs) in combination with sequence kernels have emerged as a de-facto standard.
Andreas Kothmeier   +5 more
core   +2 more sources

Dynamic Influence Networks for Rule-based Models [PDF]

open access: yes, 2017
We introduce the Dynamic Influence Network (DIN), a novel visual analytics technique for representing and analyzing rule-based models of protein-protein interaction networks.
Boutillier, Pierre   +6 more
core   +5 more sources

3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained

open access: yesScientific Reports, 2016
The potential of a spheroid tumor model composed of cells in different proliferative and metabolic states for the development of new anticancer strategies has been amply demonstrated.
M. Zanoni   +7 more
semanticscholar   +1 more source

Discriminative topological features reveal biological network mechanisms [PDF]

open access: yesBMC Bioinformatics, 2004
BackgroundRecent genomic and bioinformatic advances have motivated the development of numerous network models intending to describe graphs of biological, technological, and sociological origin.
Manuel Middendorf   +8 more
semanticscholar   +1 more source

Comparison and evaluation of statistical error models for scRNA-seq

open access: yesGenome Biology, 2021
Heterogeneity in single-cell RNA-seq (scRNA-seq) data is driven by multiple sources, including biological variation in cellular state as well as technical variation introduced during experimental processing.
S. Choudhary, R. Satija
semanticscholar   +1 more source

BioDiVinE: A Framework for Parallel Analysis of Biological Models [PDF]

open access: yes, 2009
In this paper a novel tool BioDiVinEfor parallel analysis of biological models is presented. The tool allows analysis of biological models specified in terms of a set of chemical reactions. Chemical reactions are transformed into a system of multi-affine
C. Belta   +29 more
core   +2 more sources

Internal Models in Biological Control

open access: yesAnnu. Rev. Control. Robotics Auton. Syst., 2019
Rationality principles such as optimal feedback control and Bayesian inference underpin a probabilistic framework that has accounted for a range of empirical phenomena in biological sensorimotor control.
Daniel C. McNamee, D. Wolpert
semanticscholar   +1 more source

Boolean Models of Bistable Biological Systems

open access: yes, 2009
This paper presents an algorithm for approximating certain types of dynamical systems given by a system of ordinary delay differential equations by a Boolean network model.
A. Novick   +16 more
core   +1 more source

MathSBML: a package for manipulating SBML-based biological models [PDF]

open access: yes, 2004
Summary: MathSBML is a Mathematica package designed for manipulating Systems Biology Markup Language (SBML) models. It converts SBML models into Mathematica data structures and provides a platform for manipulating and evaluating these models.
Doyle, John   +3 more
core   +2 more sources

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