Results 31 to 40 of about 26,501,681 (348)
Generic model for biological regulation [PDF]
F1000Research, 2022 Abstract Substantial portion of molecules in an organism is involved in regulation of a wide spectrum of biological processes. Several models have been presented for various forms of biological regulation, including gene expression regulation and physiological regulation; however, a generic model is missing.
openaire +2 more sources
Virology Journal, 2023 Zika virus (ZIKV) and dengue virus (DENV) share a lot of similarities being both phylogenetically closely related, share the same insect vector passage for reaching the host, affinity for the same carbohydrate receptor domains (CRDs), indicating feasible
Bruno Stein Barbosa Menechino +5 more
doaj +1 more source
R-Mixup: Riemannian Mixup for Biological Networks [PDF]
, 2023 Biological networks are commonly used in biomedical and healthcare domains to effectively model the structure of complex biological systems with interactions linking biological entities. However, due to their characteristics of high dimensionality and low sample size, directly applying deep learning models on biological networks usually faces severe ...
arxiv +1 more source
In silico design and evaluation of a multi-epitope and multi-antigenic African swine fever vaccine
ImmunoInformatics, 2022 African Swine Fever (ASF) is caused by a highly contagious and fatal hemorrhagic virus, which in 2019 alone in Asia, has killed 8 million pigs with a devastating estimated economic loss amounting to $130 billion.
Ara Karizza G. Buan +3 more
doaj
Duplication Models for Biological Networks [PDF]
Journal of Computational Biology, 2003 Are biological networks different from other large complex networks? Both large biological and non-biological networks exhibit power-law graphs (number of nodes with degree k, N(k) ~ k-b) yet the exponents, b, fall into different ranges. This may be because duplication of the information in the genome is a dominant evolutionary force in shaping ...
Linyuan Lu +3 more
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Development and validation of computational models of cellular interaction [PDF]
, 2004 In this paper we take the view that computational models of biological systems should satisfy two conditions – they should be able to predict function at a systems biology level, and robust techniques of validation against biological models must be ...
Holcombe, W.M.L. +2 more
core +1 more source
Anomalous relaxation kinetics of biological lattice-ligand binding models [PDF]
, 2002 We discuss theoretical models for the cooperative binding dynamics of ligands to substrates, such as dimeric motor proteins to microtubules or more extended macromolecules like tropomyosin to actin filaments.
Andrej Vilfan +67 more
core +3 more sources
Mechanistic models versus machine learning, a fight worth fighting for the biological community?
Biology Letters, 2018 Ninety per cent of the world's data have been generated in the last 5 years (Machine learning: the power and promise of computers that learn by example. Report no. DES4702. Issued April 2017. Royal Society).
R. Baker +3 more
semanticscholar +1 more source
Animal models in biological and biomedical research - experimental and ethical concerns.
Anais da Academia Brasileira de Ciências, 2019 Animal models have been used in experimental research to increase human knowledge and contribute to finding solutions to biological and biomedical questions.
M. Andersen, L. M. F. Winter
semanticscholar +1 more source
A study of psychiatrists’ concepts of mental illness [PDF]
, 2008 Background: There are multiple models of mental illness that inform professional and lay understanding. Few studies have formally investigated psychiatrists' attitudes.
Bowker +22 more
core +4 more sources