Results 41 to 50 of about 3,734,088 (300)
At the Biological Modeling and Simulation Frontier [PDF]
Pharmaceutical Research, 2009 We provide a rationale for and describe examples of synthetic modeling and simulation (M&S) of biological systems. We explain how synthetic methods are distinct from familiar inductive methods. Synthetic M&S is a means to better understand the mechanisms that generate normal and disease-related phenomena observed in research, and how compounds of ...
Hunt, C. Anthony +6 more
openaire +4 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman +7 more
wiley +1 more source
Kinetic hierarchy and propagation of chaos in biological swarm models [PDF]
, 2011 We consider two models of biological swarm behavior. In these models, pairs of particles interact to adjust their velocities one to each other. In the first process, called 'BDG', they join their average velocity up to some noise.
Aoki +34 more
core +4 more sources
Parasites as biological models
Parasitology, 1969 The value of metazoan parasites as models for the investigation of fundamental biological phenomena is discussed. The fields in which they are of particular value include: immunology, neuromuscular physiology, nucleo-cytoplasmic relationships, genetics, cyto-differentiation, comparative biochemistry.After reviewing some examples of experimental ...
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro +11 more
wiley +1 more source
Sodium benzoate may reduce appetite in Drosophila melanogaster through serotonin upregulation [PDF]
Archives of Biological SciencesSodium benzoate is a common artificial preservative in processed food, yet little is known about its long-term health effects. Since sodium benzoate could upregulate serotonin, we hypothesized that it may induce satiety and activate processes underlying ...
Nas John Sylvester B. +1 more
doaj +1 more source
Complex Behavior in Simple Models of Biological Coevolution
, 2006 We explore the complex dynamical behavior of simple predator-prey models of biological coevolution that account for interspecific and intraspecific competition for resources, as well as adaptive foraging behavior.
Krebs C. J. +5 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke +4 more
wiley +1 more source
Food Production, Processing and NutritionTapuy is an indigenous rice wine traditionally prepared during rituals and ceremonies in the northern regions of the Philippines. Its fermentation by-product, the Tapuy lees, is nutrient-dense but is underutilized for human consumption.
Junelle Rey C. Bacong +2 more
doaj +1 more source
Peptimapper: proteogenomics workflow for the expert annotation of eukaryotic genomes
BMC Genomics, 2019 Background Accurate structural annotation of genomes is still a challenge, despite the progress made over the past decade. The prediction of gene structure remains difficult, especially for eukaryotic species, and is often erroneous and incomplete.
Laetitia Guillot +10 more
doaj +1 more source