Results 61 to 70 of about 3,734,088 (300)

Analysis of parametric biological models with non-linear dynamics

, 2012
In this paper we present recent results on parametric analysis of biological models. The underlying method is based on the algorithms for computing trajectory sets of hybrid systems with polynomial dynamics. The method is then applied to two case studies
Asarin, Batt, Batt, Belta, Berman, Britton, Chen, Clauss, Dang, Dang, Dang, Drulhe, Ezio Bartocci, Fotiou, Garloff, Grosu, H. Prautzsch and W. Boehm, Henzinger, I. Tchoupaeva, J. Garloff, J. Garloff and A.P. Smith, Luca Bortolussi, Prajna, Romain Testylier, S. Boyd and S. Vandenberghe, Sankaranarayanan, Thao Dang, Thao Dang   +27 more
core   +3 more sources

Modeling and estimation for biological plants

, 2022
Estimating the state of a dynamic system is an essential task for achieving important objectives such asprocess monitoring, identification, and control. Unlike linear systems, no systematic method exists forthe design of observers for nonlinear systems. Although many researchers have devoted their attention to these issues for more than 30 years, there
openaire   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Effects of starter cultures on the metabolite profile, antioxidant activities, and anti-aging properties of tapuy lees

Discover Food
The Philippine rice wine (tapuy) and tapuy lees making process utilizes bubod, the traditional starter culture. The bubod contains variable number and species of microorganisms and influences the physical and chemical properties of tapuy and tapuy lees ...
Edward Kevin B. Bragais, Paul Mark B. Medina   +1 more
doaj   +1 more source

The Cordyceps Genus as a Potential Source of Bioactive Compounds for Adjuvant Cancer Therapy: A Network Pharmacology Approach

Pharmaceuticals
Background/Objectives: Cancer remains one of the leading causes of mortality globally, underscoring the need for novel therapeutic strategies capable of targeting multiple molecular pathways simultaneously.
Jose Luis Gonzalez-Llerena, Daniela Treviño-Almaguer, Jesus Alejandro Leal-Mendez, Gael Garcia-Valdez, Arely Guadalupe Balderas-Moreno, Michel Stéphane Heya, Isaias Balderas-Renteria, María del Rayo Camacho-Corona, Bryan Alejandro Espinosa-Rodriguez   +8 more
doaj   +1 more source

Semi-parametric analysis of multi-rater data [PDF]

, 2009
Datasets that are subjectively labeled by a number of experts are becoming more common in tasks such as biological text annotation where class definitions are necessarily somewhat subjective.
Girolami, M., Polajnar, T., Rogers, S.
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Epithelial–mesenchymal transition (EMT) and its role in acquired epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) chemoresistance in non-small cell lung cancer (NSCLC)

Cancer Pathogenesis and Therapy
Epithelial–mesenchymal transition (EMT) is a biological process that involves the transformation of epithelial cells into cells with a mesenchymal phenotype, enhancing their migratory and invasive capabilities.
Ma. Carmela P. Dela Cruz, Paul Mark B. Medina   +1 more
doaj   +1 more source

Bridging Mechanistic and Phenomenological Models of Complex Biological Systems

, 2016
The inherent complexity of biological systems gives rise to complicated mechanistic models with a large number of parameters. On the other hand, the collective behavior of these systems can often be characterized by a relatively small number of ...
Qiu, Peng, Transtrum, Mark K.
core   +2 more sources