Results 81 to 90 of about 3,734,088 (300)
Correction to: Rapid turnover of life-cycle-related genes in the brown algae
Genome Biology, 2019 Following publication of the original article [1], it was noticed that the author names were published with initials instead of full names. The article [1] has been updated.
Agnieszka P. Lipinska +6 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
MedicinaBackground and Objectives: Autism spectrum disorder (ASD) is a prevalent neurodevelopmental disorder with an increasing global incidence. Gut microbiota dysbiosis is believed to be playing a role in ASD pathogenesis. Fecal microbiota transplantation (FMT)
Dominykas Varnas +3 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Data-driven modelling of biological multi-scale processes
, 2015 Biological processes involve a variety of spatial and temporal scales. A holistic understanding of many biological processes therefore requires multi-scale models which capture the relevant properties on all these scales.
Hasenauer, Jan +3 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Rapid turnover of life-cycle-related genes in the brown algae
Genome Biology, 2019 Background Sexual life cycles in eukaryotes involve a cyclic alternation between haploid and diploid phases. While most animals possess a diploid life cycle, many plants and algae alternate between multicellular haploid (gametophyte) and diploid ...
Agnieszka P. Lipinska +6 more
doaj +1 more source
From Solvable to Executable Models of Biological Systems [PDF]
, 2008 Classical modeling approaches for biology are mainly grounded in mathematics, and specifically on ordinary differential equations (ODE). Process calculi-based conceptual and computational tools are an alternative and emergent approach.
Palmisano, Alida, Priami, Corrado
core
Stability of a neural network model with small-world connections
, 2004 Small-world networks are highly clustered networks with small distances among the nodes. There are many biological neural networks that present this kind of connections.
C. Aguirre +15 more
core +1 more source