Results 81 to 90 of about 10,674,828 (317)

Annual Report - Marine Biological Laboratory, 1893

, 1894
Annual report of the Marine Biological Laboratory in Woods Hole. 1893.
Marine Biological Laboratory (Woods Hole MA)
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Investigating tryptophan-producing probiotic lactic acid bacteria from Lithuanian fermented foods: functional characterization, safety evaluation, and genomic analysis

Journal of Functional Foods
This study aimed to isolate and characterize lactic acid bacteria (LAB) from traditional Lithuanian fermented foods and evaluate their probiotic potential, safety, and ability to produce tryptophan.
Ashwinipriyadarshini Megur, Kamilė Ambrutaitytė, Mikas Sadauskas, Jonita Stankevičiūtė, Rolandas Meškys, Eglė Lastauskienė, Aurelijus Burokas   +6 more
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 1903-1906

, 1907
https://hdl.handle.net/1912/21944Marine Biological Laboratory.
Marine Biological Laboratory (Woods Hole MA)
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

A novel dual DYRK1A/B inhibitor for the treatment of type 1 diabetes

Frontiers in Pharmacology
BackgroundType 1 diabetes (T1D) is an autoimmune disease that leads to the progressive destruction of pancreatic β cells, resulting in insulin deficiency and hyperglycemia. Current treatments focus on insulin replacement, but novel therapeutic approaches
Šarūnas Tumas, Jonas Mingaila, Vytautas Baranauskas, Vytautas Baranauskas, Emilija Baltrukonytė, Laurynas Orla, Jan Aleksander Krasko, Roberta Pocevičiūtė, Dina Berlina, Alexei Belenky, Maria Vilenchik, Agnė Vaitkevičienė, Olga Potapova, Aurelijus Burokas   +13 more
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 1890

, 1890
Annual report of the Marine Biological Laboratory in Woods Hole. 1890.
Marine Biological Laboratory (Woods Hole MA)
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 2002

, 2003
Annual report of the Marine Biological Laboratory in Woods Hole. 2002.
Marine Biological Laboratory (Woods Hole MA)
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source