Results 81 to 90 of about 1,977,773 (318)

Correction to: Rapid turnover of life-cycle-related genes in the brown algae

open access: yesGenome Biology, 2019
Following publication of the original article [1], it was noticed that the author names were published with initials instead of full names. The article [1] has been updated.
Agnieszka P. Lipinska   +6 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Multiclock discrete models of biological systems [PDF]

open access: yes, 2009
Modeling biological systems requires precise temporal concepts. Biological observations are often issued from discrete event measurements, which make discrete modeling especially interesting. However time is absent of these models or defined a priori.
Le Borgne, Michel   +3 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Mouse models of cancer as biological filters for complex genomic data [PDF]

open access: yes, 2010
Genetically and pathologically accurate mouse models of leukemia and lymphoma have been developed in recent years. Adoptive transfer of genetically modified hematopoietic progenitor cells enables rapid and highly controlled gain- and loss-of-function ...
Jonathan H. Schatz   +9 more
core   +1 more source

Fecal Microbiota Transplantation for Autism Spectrum Disorder in Children: Results from a Prospective Open-Label Controlled Observational Study

open access: yesMedicina
Background and Objectives: Autism spectrum disorder (ASD) is a prevalent neurodevelopmental disorder with an increasing global incidence. Gut microbiota dysbiosis is believed to be playing a role in ASD pathogenesis. Fecal microbiota transplantation (FMT)
Dominykas Varnas   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Replication Data for: "From biological data to oscillator models using SINDy" [PDF]

open access: yes
Archived version of data needed to reproduce result figures shown in the manuscript: "From biological data to oscillator models using SINDy". The data contains used experimental data which has been taken from literature (BZ reaction, glycolytic ...
Prokop, Bartosz, Gelens, Lendert
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The case for marine ecosystem models of intermediate complexity [PDF]

open access: yes, 2009
Marine ecosystem models are reasonably proficient at simulating physically-driven features such as spring blooms. However, the demands on these models are shifting to complex biological issues such as functional diversity, and changes in ecosystems and ...
Vezina, Alain   +7 more
core   +1 more source

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