Results 91 to 100 of about 1,977,773 (318)
Rapid turnover of life-cycle-related genes in the brown algae
Genome Biology, 2019 Background Sexual life cycles in eukaryotes involve a cyclic alternation between haploid and diploid phases. While most animals possess a diploid life cycle, many plants and algae alternate between multicellular haploid (gametophyte) and diploid ...
Agnieszka P. Lipinska +6 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Conservation Businesses and Conservation Planning in a Biological Diversity Hotspot [PDF]
, 2013 The allocation of land to biological diversity conservation competes with other land uses and the needs of society for development, food, and extraction of natural resources.
MacMillan, Douglas C.
core +1 more source
MoleculesThe gut microbiota produces a variety of bioactive molecules that facilitate host–microbiota interaction. Indole and its metabolites are focused as possible biomarkers for various diseases.
Arnas Kunevičius +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Bayesian network models of biological signaling pathways [PDF]
, 2006 Thesis (Ph. D.)--Massachusetts Institute of Technology, Biological Engineering Division, 2006.Includes bibliographical references (p. 153-165).Cells communicate with other cells, and process cues from their environment, via signaling pathways, in which ...
Sachs, Karen, Ph. D. Massachusetts Institute of Technology
core
A Credible-World Account of Biological Models [PDF]
, 2017 In a broad brush, biological models are often constructed in two general types: (1) as a concrete model; (2) as an abstract model. A concrete model is a material model such as model organisms, while an abstract model is a mathematical or computational ...
Tee, Sim Hui, Sim-Hui Tee
core +1 more source
Data in BriefThis strain was isolated from traditionally (homemade) fermented Lithuanian cherry tomatoes. The genome consists of 55 contigs with a total size of 3,326,119 bp, an N50 of 170738, and a GC% of 44.3 %.
Ashwinipriyadarshini Megur +2 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Computing reachable states for nonlinear biological models [PDF]
, 2011 In this paper, we describe reachability computation for continuous and hybrid systems and its potential contribution to the process of building and debugging biological models. We summarize the state-of-the-art for linear systems and then develop a novel
Colas Le Guernic +5 more
core +1 more source