Results 111 to 120 of about 859,409 (265)

Cardiovascular Changes in Animal Models of Metabolic Syndrome

Journal of Diabetes Research, 2013
Metabolic syndrome has been defined as a group of risk factors that directly contribute to the development of cardiovascular disease and/or type 2 diabetes. Insulin resistance seems to have a fundamental role in the genesis of this syndrome.
Alexandre M. Lehnen, Bruno Rodrigues, Maria Cláudia Irigoyen, Kátia De Angelis, Beatriz D’Agord Schaan   +4 more
doaj   +1 more source

Association Between Symptomatic Knee Osteoarthritis and Target Glycemic Control in Individuals With Type 2 Diabetes

Arthritis Care &Research, EarlyView.
Objective Knee osteoarthritis (OA) commonly affects individuals with type 2 diabetes (T2DM) and is associated with increased risk of diabetes‐related complications. To better understand potential mechanisms, we examined the association between symptomatic knee OA and glycemic control in individuals with T2DM.
Lauren K. King, Alanna Weisman, Baiju R. Shah, Robert Goldberg, Amish Parikh, Ian Stanaitis, Vivian Hung, Rosane Nisenbaum, Abdalmohsen Almodahka, Lorraine Lipscombe, Gillian A. Hawker   +10 more
wiley   +1 more source

Cardiovascular Surgery Residency Program: Training Coronary Anastomosis Using the Arroyo Simulator and UNIFESP Models

, 2015
OBJECTIVE: Engage the UNIFESP Cardiovascular Surgery residents in coronary anastomosis, assess their skills and certify results, using the Arroyo Anastomosis Simulator and UNIFESP surgical models. METHODS: First to 6th year residents attended a weekly
Thiago Cavalcante Vila Nova de Araújo, Araújo,Thiago Cavalcante Vila Nova de, Gomes,Walter José, André Lupp Mota, Mota,André Lupp, Caio Cesar Cardoso, Rafael Viana dos S. Coutinho, Maluf,Miguel Angel, Ademir Massarico Bras, Walter José Gomes, Cardoso,Caio Cesar, Miguel Angel Maluf, Bras,Ademir Massarico, Coutinho,Rafael Viana dos S.   +13 more
core   +1 more source

In Vivo Testing of a Second-Generation Prototype Accessory for Single Transapical Left Ventricular Assist Device Implantation

Bioengineering
A new accessory was developed to allow implantation of left ventricular assist devices (LVADs) without requiring an anastomosis to the ascending aorta. The accessory combines the LVAD inflow and outflow into a dual-lumen device.
Florian Meissner, Michelle Costa Galbas, Hendrik Straky, Heiko Vestner, Manuela Schoen, Marius Schimmel, Johanna Reuter, Martin Buechsel, Johannes Dinkelaker, Heidi Cristina Schmitz, Martin Czerny, Wolfgang Bothe   +11 more
doaj   +1 more source

Addressing Economic Insecurities Can Improve Patient‐Reported Outcomes in Lupus

Arthritis Care &Research, EarlyView.
Objective Economic insecurities, such as food, housing, transportation, and financial challenges, are modifiable risk factors and influence patient‐reported outcomes (PROs) in systemic lupus erythematosus (SLE). We examined the following: (1) associations between economic insecurities and PROs, and (2) the impact of screening and addressing economic ...
Jay Patel, Tripti Singh, Meredith Ingersoll, Shelby Gomez, Amanda Weber, Sarah E. Panzer, Sancia Ferguson, Christie M. Bartels, Shivani Garg   +8 more
wiley   +1 more source

Three-dimensional spheroid models for cardiovascular biology and pathology

Mechanobiology in Medicine
Scaffold-free three-dimensional (3D) cellular spheroid cultures better replicate the in vivo cellular microenvironments of complex tissues than traditional two-dimensional (2D) cell cultures, as they promote more intricate cell-cell and cell ...
Alanna Krug, Gabrielle Inserra, Rhonda Drewes, Amanda Krajnik, Joseph A. Brazzo, III, Thomas Mousso, Su Chin Heo, Yongho Bae   +7 more
doaj   +1 more source

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

Arthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie, Timothy Beukelman, Nicholas P. McCormick, Jeffrey R. Curtis   +3 more
wiley   +1 more source

Rat models of cardiovascular diseases

, 2009
In cardiovascular research, the rat has been the main model of choice for decades. Experimental procedures were developed to generate cardiovascular disease states in this species, such as systemic and pulmonary hypertension, cardiac hypertrophy and ...
Michael Bader, Bader, M.
core   +1 more source

Assessing the Sensitivity and the Clinical Impact of the 2023 American College of Rheumatology/EULAR Classification Criteria in Obstetric Antiphospholid Syndrome: Findings From a Multicenter Italian Cohort With a Long‐Term Follow‐Up

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...
Francesca Ruffilli, Cecilia Nalli, Francesca Crisafulli, Carlo Garaffoni, Marcello Govoni, Giulia Voltarel, Alba C. Pozzi, Beatrice Maranini, Ettore Silvagni, Alessandra Bortoluzzi, Angela Tincani   +10 more
wiley   +1 more source