Results 121 to 130 of about 23,798,154 (337)

Ultra-processed food intake and risk of cardiovascular disease: prospective cohort study (NutriNet-Santé)

British medical journal, 2019
Objective To assess the prospective associations between consumption of ultra-processed foods and risk of cardiovascular diseases. Design Population based cohort study. Setting NutriNet-Santé cohort, France 2009-18. Participants 105 159 participants aged
B. Srour, L. Fezeu, E. Kesse‐Guyot, B. Allès, C. Méjean, R. M. Andrianasolo, E. Chazelas, M. Deschasaux, S. Hercberg, P. Galan, C. Monteiro, C. Julia, M. Touvier   +12 more
semanticscholar   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Hematologic and biochemical reference values for anesthetized juvenile German crossbred farm pigs

Scientific Reports
Juvenile crossbred pigs are widely used for acute and chronic animal testing due to their anatomical and physiological resemblance to humans. They are particularly prevalent in preclinical cardiovascular research, including studies investigating ...
Florian Meissner, Johannes Dinkelaker, Alexander Maier, Jan-Steffen Pooth, Michelle Costa Galbas, Manuela Schön, David Boll, Georg Trummer, Christoph Benk, Jörg Haberstroh, Heidi Ramona Cristina Schmitz, Katharina Förster, Natalie Hoppe, Martin Büchsel, Simon Reiss, Martin Czerny, Wolfgang Bothe, Sam Brixius   +17 more
doaj   +1 more source

Genetic Animal Models of Cardiovascular Pathologies

Biomedicines
This review critically examines the evolving landscape of genetic animal models for investigating cardiovascular diseases (CVDs). We analyze established models, including spontaneously hypertensive rats, Watanabe hyperlipidemic rabbits, etc., and ...
Mikhail Blagonravov, Anna Ryabinina, Ruslan Karpov, Vera Ovechkina, Maxim Filatov, Yulia Silaeva, Sergei Syatkin, Enzo Agostinelli, Vsevolod Belousov, Andrey Mozhaev   +9 more
doaj   +1 more source

Redox stress defines the small artery vasculopathy of hypertension: how do we bridge the bench-to-bedside gap? [PDF]

, 2017
Although convincing experimental evidence demonstrates the importance of vascular reactive oxygen and nitrogen species (RONS), oxidative stress, and perturbed redox signaling as causative processes in the vasculopathy of hypertension, this has not ...
Liang, Mingyu, Montezano, Augusto C., Rios, Francisco, Touyz, Rhian M., Widlansky, Michael E.   +4 more
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

In Vitro Models of Cardiovascular Calcification

Biomedicines
Cardiovascular calcification, characterized by hydroxyapatite deposition in the arterial wall and heart valves, is associated with high cardiovascular morbidity and mortality.
Andrea Tóth, Enikő Balogh, Viktória Jeney   +2 more
doaj   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Open-source controller for dynamic cardiovascular models

HardwareX
Cardiovascular pressure sensors require dedicated, reliable, and customisable performance testing equipment. Devices available on the market, such as pulsatile pumps and pulse multipliers, offer limited adaptability to the needs of pressure sensor ...
Muhammad Farooq, Muhammad Riaz ur Rehman, Patricia Vazquez, William Wijns, Atif Shahzad, Marcin J. Kraśny   +5 more
doaj   +1 more source

Vascular Inflammation and Oxidative Stress: Major Triggers for Cardiovascular Disease

Oxidative Medicine and Cellular Longevity, 2019
Cardiovascular disease is a leading cause of death and reduced quality of life, proven by the latest data of the Global Burden of Disease Study, and is only gaining in prevalence worldwide.
S. Steven, Katie Frenis, M. Oelze, S. Kalinovic, Marin Kuntić, M. T. Bayo Jiménez, K. Vujacic-Mirski, Johanna Helmstädter, Swenja Kröller-Schön, T. Münzel, A. Daiber   +10 more
semanticscholar   +1 more source