An explainable machine learning framework for cardiovascular risk prediction using structured health data. [PDF]
Paul VV, Syed Masood JAI.
europepmc +1 more source
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou +5 more
wiley +1 more source
Risk stratification of patients with syncope in the emergency department using ECG based artificial intelligence models. [PDF]
Knudsen A +9 more
europepmc +1 more source
Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla +15 more
wiley +1 more source
Cardiovascular disease and mortality following placental abruption. [PDF]
Ananth CV +6 more
europepmc +1 more source
Resolving Heterogeneity of Targeted Lipid Nanoparticles Through Solution‐Based Biophysical Analyses
AF4‐UV‐DLS‐MALS‐SAXS resolves previously inaccessible targeted lipid nanoparticle (tLNP) subpopulations that differ in size, shape, and composition. Correlation of subpopulation‐resolved biophysical properties with in vivo RNA delivery reveals that targeted placental transfection is associated with distinct tLNP subpopulations rather than ensemble ...
Hannah C. Geisler +14 more
wiley +1 more source
A next-generation prediction risk model for acute myocardial infarction: Derivation and validation in a multi-centre cohort. [PDF]
Amorocho-Morales JD +4 more
europepmc +1 more source
Evolving Models of Cardiovascular Practices
openaire +2 more sources
Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review
Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase +6 more
wiley +1 more source
Risk factors for multimorbidity of cardiovascular diseases in the prospective Million Women Study. [PDF]
Suh JW +4 more
europepmc +1 more source

