Advances in semantic representation for multiscale biosimulation: a case study in merging models [PDF]
, 2009 As a case-study of biosimulation model integration, we describe our experiences applying the SemSim methodology to integrate independently-developed, multiscale models of cardiac circulation. In particular, we have integrated the CircAdapt model (written
Arts, Theo +3 more
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A novel closed-chest porcine model of chronic ischemic heart failure suitable for experimental research in cardiovascular disease [PDF]
, 2013 Cardiac pathologies are among the leading causes of mortality and morbidity in industrialized countries, with myocardial infarction (MI) representing one of the major conditions leading to heart failure (HF).
Antonio Amodeo +15 more
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Genetic Animal Models of Cardiovascular Pathologies
BiomedicinesThis review critically examines the evolving landscape of genetic animal models for investigating cardiovascular diseases (CVDs). We analyze established models, including spontaneously hypertensive rats, Watanabe hyperlipidemic rabbits, etc., and ...
Mikhail Blagonravov +9 more
doaj +1 more source
Association of Tenofovir Use With Risk of Incident Heart Failure in HIV-Infected Patients. [PDF]
, 2017 BackgroundThe antiretroviral medication, tenofovir disoproxil fumarate (TDF), is used by most human immunodeficiency virus-infected persons in the United States despite higher risks of chronic kidney disease.
Chen, Ruijun +7 more
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Hematologic and biochemical reference values for anesthetized juvenile German crossbred farm pigs
Scientific ReportsJuvenile crossbred pigs are widely used for acute and chronic animal testing due to their anatomical and physiological resemblance to humans. They are particularly prevalent in preclinical cardiovascular research, including studies investigating ...
Florian Meissner +17 more
doaj +1 more source
In Vitro Models of Cardiovascular Calcification
BiomedicinesCardiovascular calcification, characterized by hydroxyapatite deposition in the arterial wall and heart valves, is associated with high cardiovascular morbidity and mortality.
Andrea Tóth +2 more
doaj +1 more source
Open-source controller for dynamic cardiovascular models
HardwareXCardiovascular pressure sensors require dedicated, reliable, and customisable performance testing equipment. Devices available on the market, such as pulsatile pumps and pulse multipliers, offer limited adaptability to the needs of pressure sensor ...
Muhammad Farooq +5 more
doaj +1 more source
Risk of cardiovascular events from current, recent, and cumulative exposure to abacavir among persons living with HIV who were receiving antiretroviral therapy in the United States: a cohort study. [PDF]
, 2017 BackgroundThere is ongoing controversy regarding abacavir use in the treatment of HIV infection and the risk of subsequent development of cardiovascular disease.
Baxi, Sanjiv M +3 more
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Progress of organoid platform in cardiovascular research
Bioactive MaterialsCardiovascular disease is a significant cause of death in humans. Various models are necessary for the study of cardiovascular diseases, but once cellular and animal models have some defects, such as insufficient fidelity.
Xingchao Du +4 more
doaj +1 more source
Modelos experimentales de enfermedad cardiovascular Experimental models of cardiovascular disease
Nutrición Hospitalaria, 2007 El presente trabajo describe los modelos experimentales de utilidad clínica en el estudio de las enfermedades cardiovasculares y hace énfasis en los modelos usados para determinar los mecanismos fisiopatológicos de la aterosclerosis, así como para ...
A. Gil Hernández +3 more
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