Results 11 to 20 of about 12,735,429 (294)

Evaluation of mental models of prospective science teachers on chemical reactions [PDF]

open access: yesJournal of Pedagogical Research, 2021
The aim of this study is to examine prospective science teachers' (PSTs) mental models and meanings for the concept of chemical reaction. For this purpose, this study adopted a phenomenological research design including 48 PSTs.
Volkan Bilir, Sedat Karaçam
doaj   +1 more source

Chemical language models for de novo drug design: Challenges and opportunities [PDF]

open access: yes, 2022
Generative deep learning is accelerating de novo drug design, by allowing the generation of molecules with desired properties on demand. Chemical language models – which generate new molecules in the form of strings using deep learning – have been ...
Grisoni, Francesca; id_orcid   +2 more
core   +3 more sources

Cultivation and Imaging of S. latissima Embryo Monolayered Cell Sheets Inside Microfluidic Devices

open access: yesBioengineering, 2022
The culturing and investigation of individual marine specimens in lab environments is crucial to further our understanding of this highly complex ecosystem.
Thomas Clerc   +5 more
doaj   +1 more source

ZSCAN4 interacts with PARP1 to promote DNA repair in mouse embryonic stem cells

open access: yesCell & Bioscience, 2023
Background In eukaryotic cells, DNA double strand breaks (DSB) are primarily repaired by canonical non-homologous end joining (c-NHEJ), homologous recombination (HR) and alternative NHEJ (alt-NHEJ).
Li-Kuang Tsai   +8 more
doaj   +1 more source

Lipid Profiles of the Heads of Four Shrimp Species by UPLC–Q–Exactive Orbitrap/MS and Their Cardiovascular Activities

open access: yesMolecules, 2022
Lipids are key factors in nutrition, structural function, metabolic features, and other biological functions. In this study, the lipids from the heads of four species of shrimp (Fenneropenaeus chinensis (FC), Penaeus japonicus (PJ), Penaeus vannamei (PV),
Yongqiang Zhu   +10 more
doaj   +1 more source

Deep Generative Models Enable Navigation in Sparsely Populated Chemical Space [PDF]

open access: yes, 2021
Deep generative models are powerful tools for the exploration of chemical space, enabling the on-demand gener- ation of molecules with desired physical, chemical, or biological properties.
R. Greg, Stacey   +3 more
core   +1 more source

Reduced-Precision Chemical Kinetics in Atmospheric Models

open access: yesAtmosphere, 2022
Modelling atmospheric composition and climate change on the global scale remains a great scientific challenge. Earth system models spend up to 85% of their total required computational resources on the integration of atmospheric chemical kinetics.
Kyriacos Sophocleous   +1 more
doaj   +1 more source

Modelling the Chemical Evolution [PDF]

open access: yesProceedings of the International Astronomical Union, 2009
AbstractAdvanced observational facilities allow to trace back the chemical evolution of the Universe, on the one hand, from local objects of different ages and, secondly, by direct observations of redshifted objects. The chemical enrichment serves as one of the cornerstones of cosmological evolution.
Recchi, Simone, Hensler, Gerhard
openaire   +3 more sources

Standardizing chemical compounds with language models

open access: yesMachine Learning: Science and Technology, 2023
With the growing amount of chemical data stored digitally, it has become crucial to represent chemical compounds accurately and consistently. Harmonized representations facilitate the extraction of insightful information from datasets, and are ...
Miruna T Cretu   +5 more
doaj   +1 more source

A Novel Modelling Process in Chemistry: Merging Biological and Mathematical Perspectives to Develop Modelling Competences

open access: yesEducation Sciences, 2021
Models are essential in science and therefore in scientific literacy. Therefore, pupils need to attain competency in the appropriate use of models. This so-called model–methodical competence distinguishes between model competence (the conceptual part ...
Vanessa Lang   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy