Results 221 to 230 of about 12,735,429 (294)

ADMET-XSpec: A Tool for Systematic Cross-Species Data Integration in ADMET Prediction. [PDF]

Chem Res Toxicol
Rybka H, Masztalerz K, Podlewska S.
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Non-Destructive Analysis of Phenolic and Flavonoid Contents in Medicinal Plant Powders Using Hyperspectral Imaging and Variable Selection. [PDF]

Anal Sci Adv
Joshi R, Kholiya S, Pandey H, Singh M, Tiwari A, Lim J, Sathasivam R, Faqeerzada MA, Park SU, Cho BK.   +9 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Integrating chemical structures as treatments improves representations of microscopy images for morphological profiling. [PDF]

PLoS Comput Biol
Yu Y, Hayir E, Tenenholtz N, Mackey L, Wei Y, Alvarez-Melis D, Amini AP, Lu AX.   +7 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Machine Learning of Temperature-Dependent Chemical Kinetics Using Parallel Droplet Microreactors. [PDF]

Adv Sci (Weinh)
Saita M, Hori Y.
europepmc   +1 more source

A Review of Machine Learning and AI Applications in Enhancing HACCP Systems for Ice Cream Manufacturing. [PDF]

Foods
Gaona Hernandez JP, Olapade GM, Cho HS, Jung HM, Lee MH, Lee WY.   +5 more
europepmc   +1 more source

Development of a chemometric platform for mid-infrared fermentation monitoring. [PDF]

Sci Rep
Torres-Acosta MA, Mohan N, Yang Y, Allen J, Ward JM, Lye GJ.   +5 more
europepmc   +1 more source

Multiclass Machine Learning-Based Discovery of Novel Scaffold Inhibitors Targeting ALK. [PDF]

Pharmaceuticals (Basel)
Haque MA, Jamal QMS, Ahmad K, Binsuwaidan R, Alshammari N, Saeed M, Kim JJ, Danishuddin.   +7 more
europepmc   +1 more source