Results 241 to 250 of about 1,458,211 (268)
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Issues in Mental Health Nursing, 1985
(1985). A Genetic Model of Anxiety. Issues in Mental Health Nursing: Vol. 7, No. 1-4, pp. 159-199.
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(1985). A Genetic Model of Anxiety. Issues in Mental Health Nursing: Vol. 7, No. 1-4, pp. 159-199.
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Genetic models of schizophrenia
Acta Psychiatrica Scandinavica, 1982Multiple threshold models of inheritance are applied to a large sample of Franz Kallmann's (1938) pedigree data on schizophrenia. Paranoid and nonparanoid subtypes are represented in the models at different thresholds on a continuum of genetic‐environmental liability. Single major locus and multifactorial‐polygenic inheritance are ruled out as modes of
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Some Models of Genetic Selection
Biometrics, 1979This paper begins with a description of the classical theory of viability selection in which probabilities that individuals of various genotypes survive are in proportions that do not change with time and are independent of population structure. Salient features of viability selection with one and two loci are reviewed.
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Adapting genetic regulatory models by genetic programming
Biosystems, 2004In this paper, we focus on the task of adapting genetic regulatory models based on gene expression data from microarrays. Our approach aims at automatic revision of qualitative regulatory models to improve their fit to expression data. We describe a type of regulatory model designed for this purpose, a method for predicting the quality of such models ...
R, Eriksson, B, Olsson
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Genetic algorithm for system modelling
2017 9th International Conference on Electronics, Computers and Artificial Intelligence (ECAI), 2017The process of modeling of a real system usually implies an iterative approach where an initial model is incrementally modified in order to increase its accuracy with regard to available experimental data. Many approaches are discussed in the literature, among which some are based on Artificial Intelligence techniques.
Marius Olteanu +3 more
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Schizophrenia: a Study of Genetic Models
Human Heredity, 1979The likelihoods of observing 25 four-generational families of schizophrenics comprising 1,333 individuals have been calculated on the basis of 12 different genetic models and one control 'sporadic' model. The control model gave a log10 likelihood (L), of -240.92. Five of the genetic models were definitely excluded as incompatible with certain pedigrees.
Q, Debray, V, Caillard, J, Stewart
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Genetics and animal models of hypoparathyroidism
Trends in Endocrinology & Metabolism, 2001Hypoparathyroidism is a heterogeneous group of disorders with diverse etiologies. During the past decade, major advances have been made towards unraveling the precise cellular and molecular mechanisms that underlie the pathogenesis of this endocrinopathy.
N, Garfield, A C, Karaplis
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1992
Abstract Certain features of the epidemiology of neural tube defects are consistent with a genetic component in their aetiology. First, concordance rates for neural tube defects are significantly higher in twin pairs of like sex than in twin pairs of unlike sex (Chapter 11). Thus, it is likely that monozygotic twins are concordant for
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Abstract Certain features of the epidemiology of neural tube defects are consistent with a genetic component in their aetiology. First, concordance rates for neural tube defects are significantly higher in twin pairs of like sex than in twin pairs of unlike sex (Chapter 11). Thus, it is likely that monozygotic twins are concordant for
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Alcohol and genetics: New models
American Journal of Medical Genetics, 2002AbstractAlcoholism is a complex genetic trait; susceptibility is influenced by multiple genes of small effect. To pursue mechanistic studies, genetic animal models have been used. These models are partial, each addressing one or more of the contributing traits rather than the disease as a whole.
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2009
Abstract The “Fisherian” optimality approach determines the optimal combination of trait values but not the evolutionary trajectory nor, in general, the variation to be expected about the optimal combination. Invasibility analysis is also primarily concerned with the Evolutionarily Stable Strategy (ESS) values; though assuming clonal ...
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Abstract The “Fisherian” optimality approach determines the optimal combination of trait values but not the evolutionary trajectory nor, in general, the variation to be expected about the optimal combination. Invasibility analysis is also primarily concerned with the Evolutionarily Stable Strategy (ESS) values; though assuming clonal ...
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