Results 231 to 240 of about 1,458,211 (268)
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Pharmacogenomics, 2002
The inference of genetic interactions from measured expression data is one of the most challenging tasks of modern functional genomics. When successful, the learned network of regulatory interactions yields a wealth of useful information. An inferred genetic network contains information about the pathway to which a gene belongs and which genes it ...
E P, van Someren +3 more
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The inference of genetic interactions from measured expression data is one of the most challenging tasks of modern functional genomics. When successful, the learned network of regulatory interactions yields a wealth of useful information. An inferred genetic network contains information about the pathway to which a gene belongs and which genes it ...
E P, van Someren +3 more
openaire +2 more sources
British Journal of Psychiatry, 1976
SummaryAn analysis of recently published family history data on rapid eye movement (REM) narcolepsy was undertaken to determine the goodness-of-fit of a multifactorial (MF) model of inheritance. The analysis revealed that a two-threshold MF model can successfully account for the prevalence of REM narcolepsy and other disorders of excessive sleep (DES ...
J F, Leckman, E S, Gershon
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SummaryAn analysis of recently published family history data on rapid eye movement (REM) narcolepsy was undertaken to determine the goodness-of-fit of a multifactorial (MF) model of inheritance. The analysis revealed that a two-threshold MF model can successfully account for the prevalence of REM narcolepsy and other disorders of excessive sleep (DES ...
J F, Leckman, E S, Gershon
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Genetic Models in Pathogenesis
Annual Review of Genetics, 2004▪ Abstract  To decipher the complexity of host-pathogen interactions the widest possible range of model hosts and of analytical methods is required. As some virulence mechanisms and certain host responses have been conserved throughout evolution, even simple organisms can be used as model hosts to help our understanding of infectious diseases.
Elizabeth, Pradel, Jonathan J, Ewbank
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Mathematical Proceedings of the Cambridge Philosophical Society, 1962
Wright (14), Feller (2) and others have proposed various stochastic models of genetics to study the fluctuations of gene frequency under the influence of mutation and selection. One of their simplest models has the following structure. There are a fixed numberNof gametes each of which may be of two typesaorA.
Karlin, S., McGregor, J.
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Wright (14), Feller (2) and others have proposed various stochastic models of genetics to study the fluctuations of gene frequency under the influence of mutation and selection. One of their simplest models has the following structure. There are a fixed numberNof gametes each of which may be of two typesaorA.
Karlin, S., McGregor, J.
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Genetic models of carcinogenesis
Human Pathology, 1983The major genetic models of carcinogenesis are critically reviewed to determine their validity and relevance for clinical and experimental oncologists. Of major concern are the "two-hit" theory of Knudson and the host resistance system of Matsunaga. These models may be used to explain the pathobiologic peculiarities of human neoplasms, particularly ...
R P, Bolande, M J, Vekemans
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Genetic polymorphisms and additive genetic models
Behavior Genetics, 1985The degree of genetic dissimilarity between inbred strains or substrains of mice may be estimated from available data concerning biochemical and immunological polymorphisms. Dissimilarities between substrains are bimodally distributed, suggesting that both genetic drift and contamination are responsible for substrain differences.
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Genetic Programming in Economic Modelling
2005 IEEE Congress on Evolutionary Computation, 2005Typically, economists develop models by first selecting a model structure based on theoretical considerations and equilibrium conditions, followed by parameter estimation from available data. As more and more data become available about economic processes, the question arises whether it is possible to obtain models in which "data speak for themselves",
Korneel Duyvesteyn, Uzay Kaymak
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Models of Genetic Recombination
Annual Review of Microbiology, 1974It will be my intention to compare established and recently proposed models for . genetic recombination, with special attention to the separate component principles they contain and the function ofthese principles in the various models. As increasing attention has been paid to realistic details of DNA structure and enzymology, recombination models have
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Empirical Modelling of Genetic Algorithms
Evolutionary Computation, 2001This paper addresses the problem of reliably setting genetic algorithm parameters for consistent labelling problems. Genetic algorithm parameters are notoriously difficult to determine. This paper proposes a robust empirical framework, based on the analysis of factorial experiments.
Richard Myers, Edwin R. Hancock
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Characteristics of genetic epidemiology and genetic models for vitiligo
Journal of the American Academy of Dermatology, 2004Vitiligo occurs with a frequency of 0.1% to 2% in various populations and is classified into several subtypes by its clinical presentation. Although genetic factors are thought to be involved in the cause of vitiligo, the genetic models for different phenotypes of vitiligo are unknown.Our purpose was to explore potential genetic models for different ...
Xue-Jun, Zhang +11 more
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