Results 41 to 50 of about 3,383,156 (274)
Statistical Modeling of Spatial Extremes [PDF]
The areal modeling of the extremes of a natural process such as rainfall or temperature is important in environmental statistics; for example, understanding extreme areal rainfall is crucial in flood protection. This article reviews recent progress in the statistical modeling of spatial extremes, starting with sketches of the necessary elements of ...
A. C. Davison+2 more
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Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
Comparing estimates of climate change impacts from process-based and statistical crop models
The potential impacts of climate change on crop productivity are of widespread interest to those concerned with addressing climate change and improving global food security.
David B Lobell, Senthold Asseng
doaj +1 more source
Measuring the Quality of Multivariate Statistical Models
Assessing the quality of a statistical model is very important, since it is crucial for the utility of the modelling process’ outcome. There are many different ways of measuring statistical models quality.
Michał Trzęsiok
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Statistical Models for Company Growth [PDF]
Minor changes, submitted to Physica ...
Wyart, Matthieu, Bouchaud, Jean-Philippe
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The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti+3 more
wiley +1 more source
AUTOMATED CONSTRUCTION OF 3D STATISTICAL SHAPE MODELS
Automated segmentation of medical images is a difficult task because of the complexity of anatomic structures, inter-patient variability, and imperfect image acquisition.
Tomaž Vrtovec+4 more
doaj +1 more source
A Statistical Model for Helices with Applications [PDF]
Summary Motivated by a cutting edge problem related to the shape of -helices in proteins, we formulate a parametric statistical model, which incorporates the cylindrical nature of the helix. Our focus is to detect a “kink,” which is a drastic change in the axial direction of the helix.
Mardia, KV, Sriram, K, Deane, CM
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The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens+8 more
wiley +1 more source
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink+6 more
wiley +1 more source