Results 41 to 50 of about 1,072,338 (311)

Theoretical analysis of serrated chip formation based on ideal models in high speed cutting

open access: yes, 2010
In this paper, two ideal formation models of serrated chips, the symmetric formation model and the unilateral right-angle formation model, have been established for the first time. Based on the ideal models and related adiabatic shear theory of serrated
Gao, Chongyang   +5 more
core   +1 more source

“What you feel under your hands”: exploring professionals’ perspective of somatic dysfunction in osteopathic clinical practice—a qualitative study

open access: yesChiropractic & Manual Therapies, 2022
Background Despite controversy regarding its validity and clinical usefulness, manual examination findings still have an important role for manipulative therapies. As an example, somatic dysfunction (SD) remains central to osteopathic practice.This study
Lorenzo Arcuri   +5 more
doaj   +1 more source

Ecological Drivers of Community Cohesion

open access: yesmSystems, 2023
From protocellular to societal, networks of living systems are complex and multiscale. Discerning the factors that facilitate assembly of these intricate interdependencies using pairwise interactions can be nearly impossible.
Chaitanya S. Gokhale   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A theoretical model of anaphase

open access: yesMathematical Biosciences
This paper develops a theory for anaphase in cells. After a brief description of microtubules, the mitotic spindle and the centrosome, a mathematical model for anaphase is introduced and developed in the context of the cell cytoplasm and liquid crystalline structures.
Sleeman, Brian D., Stewart, Iain W.
openaire   +4 more sources

Synthetic Mutualism and the Intervention Dilemma

open access: yesLife, 2019
Ecosystems are complex networks of interacting individuals co-evolving with their environment. As such, changes to an interaction can influence the whole ecosystem. However, to predict the outcome of these changes, considerable understanding of processes
Jai A. Denton, Chaitanya S. Gokhale
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

From theoretical stellar spectra to realistic models of the Milky Way : a never ending Odyssey [PDF]

open access: yes, 2007
The last chapter is dedicated to the compilation of the results and the discussion about the success of - but also about the problems that have arisen during - and in part also survived - this work. The main goal of this thesis was, firstly, to convert
Ammon, Karin
core   +1 more source

Theoretical Challenges for Distance Education in the 21st Century: A shift from structural to transactional issues

open access: yesInternational Review of Research in Open and Distributed Learning, 2000
The premise of this article is that theoretical frameworks and models are essential to the long-term credibility and viability of a field of practice. In order to assess the theoretical challenges facing the field of distance education, the significant ...
Randy Garrison
doaj   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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