Results 61 to 70 of about 4,232,997 (293)

Stresses in silos: Comparison between theoretical models and new experiments

open access: yes, 1999
We present precise and reproducible mean pressure measurements at the bottom of a cylindrical granular column. If a constant overload is added, the pressure is linear in overload and nonmonotonic in the column height. The results are {\em quantitatively}
A. V. Tkachenko   +33 more
core   +1 more source

Theoretical connections between mathematical neuronal models corresponding to different expressions of noise [PDF]

open access: yes, 2016
Identifying the right tools to express the stochastic aspects of neural activity has proven to be one of the biggest challenges in computational neuroscience.
Dumont, Grégory   +2 more
core   +4 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Financial correlations at ultra-high frequency: theoretical models and empirical estimation

open access: yes, 2011
A detailed analysis of correlation between stock returns at high frequency is compared with simple models of random walks. We focus in particular on the dependence of correlations on time scales - the so-called Epps effect.
A. Lo   +24 more
core   +2 more sources

Time Travel and the Immutability of the Past within B-Theoretical Models [PDF]

open access: yes, 2018
The goal of this paper is to defend the general tenet that time travelers cannot change the past within B-theoretical models of time, independently of how many temporal dimensions there are.
Andreoletti, Giacomo, Torrengo, Giuliano
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Assessing Mathematics Teachers’ Dispositions

open access: yesJournal of Business and Social Review in Emerging Economies, 2020
The study was aimed at comparison mathematics teacher’s dispositions at secondary level. The research was conducted to distinguish the difference of disposition among teachers on male and female basis as well as on their academic qualification base.
Khadijah Batool   +2 more
doaj   +1 more source

Computational studies of biomembrane systems: Theoretical considerations, simulation models, and applications

open access: yes, 2013
This chapter summarizes several approaches combining theory, simulation and experiment that aim for a better understanding of phenomena in lipid bilayers and membrane protein systems, covering topics such as lipid rafts, membrane mediated interactions ...
Deserno, Markus   +4 more
core   +1 more source

Lithium Depletion Boundary in a Pre-Main Sequence Binary System [PDF]

open access: yes, 2002
A lithium depletion boundary is detected in HIP 112312 (GJ 871.1 A and B), a \~12 Myr old pre-main sequence binary system. A strong (EW 300 mA) Li 6708 A absorption feature is seen at the secondary (~M4.5) while no Li 6708 A feature is detected from the ...
B. Zuckerman   +7 more
core   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy