Results 71 to 80 of about 11,141,407 (303)
Giornale di Clinica Nefrologia e Dialisi, 2018 non disponibile (nursing)
S. Brenna, A. Oliveira Silva
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
An intrinsic algorithm for computing geodesic distance fields on triangle meshes with holes
, 2012 Singapore National Research Foundation Interactive Digital Media RD Program [NRF2008IDM-IDM004-006]; NSFC [61100105, 61100107]; Natural Science Foundation of Fujian Province of China [2011J05007]As a fundamental concept, geodesics play an important role ...
He, Ying +5 more
core +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
On elliptic quantum integrability: vertex models, solid-on-solid models and spin chains [PDF]
, 2016 In this thesis the topic of quantum integrability is investigated, with the elliptic case constituting the core of the thesis. The first part of the thesis is about the exact computation of the partition function governing a six-vertex or solid-on-solid ...
Sub String Theory Cosmology and ElemPart +2 more
core
, 2022 Prejudice and bias-motivated aggression (BMA) are pervasive social problems. Scholars have tested numerous competing theoretical models to demonstrate the key predicates of prejudice and BMA, including intergroup contact, dual process (i.e., right-wing ...
Williamson, H, Pauwels, LJR
core +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source