Results 81 to 90 of about 11,550,945 (305)
Inspired by the conundrum of the gravitational event GW190814, which brings to light the coalescence of a 23 M _⊙ black hole with a yet-to-be-determined secondary component, we look to modeling compact objects within the framework of $f({ \mathcal Q ...
Sunil Kumar Maurya +4 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Protocol for bilateral oophorectomy in mice: a reliable and cost-effective model for promoting an obesogenic state [PDF]
Purpose: To describe a low-cost bilateral oophorectomy technique and evaluate its effects on adiposity and metabolic alterations in female mice. Methods: An experimental design was used with 16 female mice divided into two groups: control (laparotomy; n
Juliana Andrade Pereira +5 more
doaj +2 more sources
Assessing Mathematics Teachers’ Dispositions
The study was aimed at comparison mathematics teacher’s dispositions at secondary level. The research was conducted to distinguish the difference of disposition among teachers on male and female basis as well as on their academic qualification base.
Khadijah Batool +2 more
doaj +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Resumo OBJETIVO Produzir uma reflexão sobre a capacidade do diagrama V de integrar os conhecimentos teóricos-conceituais e metodológicos obtidos de sistemas, modelos e teorias complexas e não explicitamente identificáveis.
Marcos Antônio Gomes Brandão +4 more
doaj +1 more source
Steam engine parts lists and descriptions, 2004
Historic Steam Models Working Masterpieces in ...
Steam Models Co
core

