Results 151 to 160 of about 32,339,977 (323)
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz+5 more
wiley +1 more source
Fused in sarcoma (FUS) inhibits milk production efficiency in mammals
Efficient milk production in mammals confers evolutionary advantages by facilitating the transmission of energy from mother to offspring. However, the regulatory mechanism responsible for the gradual establishment of milk production efficiency in mammals,
Haili Shao+15 more
doaj +1 more source
An Electron Model Fixed Field Alternation Gradient Accelerator
F. T. Cole+4 more
openalex +2 more sources
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia+5 more
wiley +1 more source
On the Spatial Distribution of Galaxies: a Specific Model.
Jerzy Neyman+2 more
openalex +1 more source
ON THE MACROMOLECULAR STRUCTURE OF DEOXYRIBONUCLEIC ACID: AN INTERRUPTED TWO-STRAND MODEL [PDF]
Cees Dekker, H. K. Schachman
openalex +1 more source
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur+5 more
wiley +1 more source
Inhomogeneous Stellar Models. V. a. Solar Model with Convective Envelope and Inhomogeneous Interior.
M. Schwarzschild+2 more
openalex +1 more source