Results 81 to 90 of about 23,153,291 (313)
AnimalsIsoorientin (ISO) is a natural lignan glycoside flavonoid found in various plants, including Charcot and Stonecrop. ISO exhibits diverse physiological and pharmacological effects, such as antioxidative, anti-inflammatory, hepatoprotective, antiviral ...
Zilong Meng +7 more
doaj +1 more source
Energies, 2018 Growing home comfort is causing increasing energy consumption in residential buildings and a consequent stress in urban medium and low voltage distribution networks.
Salvatore Favuzza +6 more
doaj +1 more source
Hybrid Predictive Model: When an Interpretable Model Collaborates with a Black-box Model [PDF]
arXiv, 2019 Interpretable machine learning has become a strong competitor for traditional black-box models. However, the possible loss of the predictive performance for gaining interpretability is often inevitable, putting practitioners in a dilemma of choosing between high accuracy (black-box models) and interpretability (interpretable models).
arxiv
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Hierarchical Models as Marginals of Hierarchical Models
, 2016 We investigate the representation of hierarchical models in terms of marginals of other hierarchical models with smaller interactions. We focus on binary variables and marginals of pairwise interaction models whose hidden variables are conditionally ...
Montufar, Guido, Rauh, Johannes
core +1 more source
Models as hypothesis generators and models as roadmaps [PDF]
, 2010 In this reply to Kroll, Van Hell, Tokowicz and Green (this issue) we present an analysis of the citations made to the Revised Hierarchical Model (RHM).
Brysbaert, Marc +2 more
core +2 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Fast Calculation Methods in Collective Dynamical Models of Beam/Plasma Physics
, 2002 We consider an application of modification of our variational-wavelet approach to some nonlinear collective model of beam/plasma physics: Vlasov/Boltzmann-like reduction from general BBGKY hierachy related to modeling of propagation of intense charged ...
Antonina N. Fedorova +2 more
core +2 more sources
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Trust the Model When It Is Confident: Masked Model-based Actor-Critic [PDF]
arXiv, 2020 It is a popular belief that model-based Reinforcement Learning (RL) is more sample efficient than model-free RL, but in practice, it is not always true due to overweighed model errors. In complex and noisy settings, model-based RL tends to have trouble using the model if it does not know when to trust the model.
arxiv