Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
Evidence for environmental filtering and limiting similarity depends on spatial scale and dissimilarity metrics. [PDF]
Perez-Navarro MA +4 more
europepmc +1 more source
Model comparison of the dark matter profiles of Fornax, Sculptor, Carina and Sextans [PDF]
Maarten A. Breddels, Amina Helmi
openalex +1 more source
Enzyme‐Regulated Extended Swelling of Hydrogels for Dehiscence‐Less Tissue Expansions
An interpenetrating hydrogel network with swelling under regulation by enzymatic degradation (INSURED) is fabricated to avoid dehiscence. INSURED remains structurally intact post‐implantation, while HYAL injection enables control over the onset and rate of swelling.
Byung Ik Park +10 more
wiley +1 more source
The nature of phantom dark energy and its relation to time crystals. [PDF]
Mersini-Houghton L.
europepmc +1 more source
Solvable k-essence cosmologies and modified Chaplygin gas unified models of dark energy and dark matter [PDF]
M. Sharif +3 more
openalex +1 more source
This study demonstrates that pulsed potential electrolysis significantly improves CO2 reduction performance on copper‐nitrogen doped carbon electrodes. The formation of cationic copper sites and metallic clusters as a function of applied intermittent potential leads to notable selectivity changes compared to potentiostatic reduction.
Dorottya Hursán +13 more
wiley +1 more source
Probing ultrafast foam homogenization with grating-based X-ray dark-field imaging. [PDF]
Wegert L +17 more
europepmc +1 more source
Performance of the Optimized Post-Zel'dovich Approximation for Cold Dark Matter Models in Arbitrary FLRW Cosmologies [PDF]
Takashi Hamana
openalex +1 more source

