Results 191 to 200 of about 1,986,272 (219)

Human Induced Pluripotent Stem Cells in Rare Neurological Disorders: Opportunities and Challenges for Disease Modeling and Drug Discovery. [PDF]

Stem Cells Int
Harej Hrkać A, Rački V, Belančić A, Kriz J, Vitezić D, Mršić-Pelčić J, Acharya G, Varshney M, Pilipović K.   +8 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Organoids and organs-on-a-chip as new approach methodologies at the convergence of cell biology and bioengineering. [PDF]

Cell Stem Cell
Tavakol DN, Mendonca D, Baldassarri I, Maletic-Savatic M, Vunjak-Novakovic G.   +4 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Theratyping for personalized medicine across cystic fibrosis disease models. [PDF]

Commun Med (Lond)
Bezzerri V, Gunawardena T, Gonska T, Chan AP, Salih R, Lucca F, Moraes TJ, Freedman SD, Cipolli M.   +8 more
europepmc   +1 more source

Human Organoids in Infectious Disease Research: From Host-Pathogen Interactions to Vaccine Development. [PDF]

Vaccines (Basel)
Zielinska D, Fol M, Druszczynska M.
europepmc   +1 more source

Special Issue "Zebrafish: A Model Organism for Human Health and Disease: 2nd Edition". [PDF]

Int J Mol Sci
Kanungo J.
europepmc   +1 more source

Preclinical models of COPD: a state of the art review. [PDF]

Eur Respir J
Polverino F, Benam KH, Cloonan SM, Curtis JL, Gaggar A, Kheradmand F, Lehmann M, Neptune E, Raju SV, Rojas-Quintero J, Sauler M, Tesfaigzi Y, Yildirim AÖ, Zhou AX, Sin DD.   +14 more
europepmc   +1 more source

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Epigenetics: Future Prospective in Human Disorders and Therapeutics

Medical Epigenetics, 2021
Shriram N Rajpathak
exaly