Results 121 to 130 of about 266,590 (312)

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source

The leadership role of nurse educators in mental health nursing

, 2015
Leadership behaviors and actions influence others to act, and leadership in clinical practice is an important mediator influencing patient outcomes and staff satisfaction.
Escott, Phil, Sayers, Jan M. (R15065), Lopez, Violeta, Howard, Patricia B., Cleary, Michelle (R15004)   +4 more
core   +1 more source

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

Advanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao, Hai‐Jin Zeng, Zun Wang, Chun‐Gu Hong, Yi‐Juan Tan, Yan‐Xin Duan, Jing‐Yao Luo, Ming‐Jie Luo, Yi‐Wei Liu, Xin Wang, Yi Luo, Teng‐Fei Wan, Yong Zhou, Zheng‐Guang Wang, Guo‐Wen Hu, Hao Yin, Xin‐Yue Hu, Zhen‐Xing Wang, Ze‐Hui He, Si‐Yi Cheng, Wei Du, Zhe Guan, Hai‐Li Lang, Hong‐Ji Liu, Jia Cao, Peng Chen, Jiang‐Hua Liu, Hui Xie, Chun‐Yuan Chen   +28 more
wiley   +1 more source

A neurosurgical nursing training system based on 3D printing models: practice and exploration of precision medicine

BMC Nursing
Background In recent years, the concept of precision medicine has gradually permeated the field of nursing, presenting new challenges for neurosurgical nursing staff.
Keqiong Lv, Zigang Yuan, Qiong Chen, Zhaojun Wang, Jianli Wang, Jinli Miao, Wenmin Wang, Bing Xu   +7 more
doaj   +1 more source

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

Advanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv, Yi Liu, Ning Xu, Xiao Zhang, Yaming Yang, Chengyao Li, Hanhai Mao, Mingyuan Liu, Xiaolei Liu   +8 more
wiley   +1 more source

A Model for Promote and Strengthen Individual/ Family Health: McGill Nursing Model

Florence Nightingale Journal of Nursing, 2019
With advances in science, the nursing profession has become mandatory to create their own unique the content of scientifi c knowledge. In this context, the nursing leaderships emphasized the importance of development models and theories to contribute ...
Nur Elçin BOYACIOĞLU, Yasemin KUTLU
doaj  

Family-Centered Care in Pediatric Nursing: A Systematic Review of Models and Effectiveness

Journal of Infant, Child and Adolescent Health
Purpose: In contemporary healthcare, the paradigm of family-centered care has emerged as a pivotal framework within the realm of pediatric nursing. This review aims to explore various family-centered care models in pediatric nursing to determine their ...
Raheleh Sabetsarvestani
doaj   +1 more source

Nursing handover research project: How is nursing handover talked about in the literature? [PDF]

, 2010
Aim The aim of this research project is to explore how nursing handover is talked about within current, scholarly, peer reviewed, published nursing literature from 2004-2010. Background Part of most nurses’ daily reality is nursing handover.
Wallis, Sharyn
core  

Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning

Advanced Science, EarlyView.
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen, Jiahui Xie, Yi Liao, Junyu Li, Longqi Liu, Xin Gao, Hongmin Cai   +6 more
wiley   +1 more source

Chronic disease management models in nursing homes: a scoping review. [PDF]

BMJ Open, 2020
Boscart V, Crutchlow LE, Sheiban Taucar L, Johnson K, Heyer M, Davey M, Costa AP, Heckman G.   +7 more
europepmc   +1 more source