Results 41 to 50 of about 8,304,357 (304)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
, 1993 Pretende suscitar en los lectores interés por la historia al presentarla como un desarrollo coherente y vivo de las actuaciones humanas. Es decir, que comprendan cómo la vida en familia, la agricultura, la guerra, la religión y la industria han ido cambiado a lo largo de los siglos XIX y XX hasta dar forma a la actual sociedad británica.
Speed, Peter, Speed, Mary
openaire +3 more sources
Catacomb Rediscoveries in the Central Mediterranean (16th–20th Century): An Overview
HistoriesThis article focuses on the rediscovery of catacombs in the central Mediterranean and explores some of this historiographic heritage through different kinds of documents in order to present some interesting results regarding human and cultural ...
Chiara Cecalupo
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Archaeologia Historica, 2016 Cieľom predloženého príspevku bola dokumentácia zaniknutých cestných reliktov na trase stavby diaľnice D3 Svrčinovec – Skalité, analýza ich tvarov a interpretácia v kultúrno-historickom kontexte.
Marek Vojteček, Adrián Nemergut
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Malé Šance a Valy v Čiernom : príspevok k poznaniu pevnostného systému Jablunkovského priesmyku
Archaeologia Historica, 2016 Jablunkovský priesmyk predstavoval strategický bod v uhorsko-sliezskom pohraničí. Snahy o zabezpečenie tohto priestoru začali už v 16. storočí. Počas dvoch storočí tu bol vybudovaný rozsiahly systém samostatných vojenských opevnení rôznych kategórií ...
Marek Vojteček
doaj +1 more source
Frontiers in Pediatrics, 2020 Background: A crucial aspect of the 2019 coronavirus disease (COVID-19) pandemic was the psychological impact on the population. Most countries issued restrictive laws to reduce community-based viral spread.
Stefano Passanisi +8 more
doaj +1 more source
The Modern in Hidehiro Higami : His criticism and struggles with the modern world [PDF]
, 2009 Hidehiro Higami (1911 〜 1986) was a scholar of German literature who devoted himself to the translation of Nietzsche and research into Nietzsche’s work. He explored religion in the modern age.
ムラマツ, ススム +2 more
core +1 more source