Results 31 to 40 of about 413,917 (262)

Asymmetric aging effect on modern microprocessors

open access: yesMicroelectronics Reliability, 2021
Reliability is a crucial requirement in any modern microprocessor to assure correct execution over its lifetime. As mission critical components are becoming common in commodity systems; e.g., control of autonomous cars, the demand for reliable processing has even further heightened.
Freddy Gabbay, Avi Mendelson
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Plantes médicinales et régime alimentaire

open access: yesArchéopages, 2016
Among the vestiges of modern age discovered during the excavations of the Cistercian abbey of Clairefontaine, located in the province of Luxembourg on the present Belgian territory, the latrines provided rich archaeological material, including well ...
Sidonie Preiss
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The Real World around me – Life within the Pixel? [PDF]

open access: yesIn Medias Res, 2015
Modern era, the famous 21st century is full of options. Never more features and never greater alienation. Is it really so? While living in their standard-progress that, but when it towered over the black shadow, and when you are able to save someone’s ...
Aleksandra Bokan
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Catacomb Rediscoveries in the Central Mediterranean (16th–20th Century): An Overview

open access: yesHistories
This article focuses on the rediscovery of catacombs in the central Mediterranean and explores some of this historiographic heritage through different kinds of documents in order to present some interesting results regarding human and cultural ...
Chiara Cecalupo
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

The modern age

open access: yes, 1993
Pretende suscitar en los lectores interés por la historia al presentarla como un desarrollo coherente y vivo de las actuaciones humanas. Es decir, que comprendan cómo la vida en familia, la agricultura, la guerra, la religión y la industria han ido cambiado a lo largo de los siglos XIX y XX hasta dar forma a la actual sociedad británica.
Speed, Peter, Speed, Mary
openaire   +3 more sources

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