Results 51 to 60 of about 7,576,134 (299)

Politainment on Twitter: Engagement in the Spanish Legislative Elections of April 2019

open access: yesMedia and Communication, 2023
The mediatisation of politics is based on the logic of spectacle. Politainment defines the phenomenon in which political information is trivialised by the hybrid narratives in which it is included and its anecdotal tone, with the aim of reaching an ...
Salomé Berrocal-Gonzalo   +2 more
doaj   +1 more source

An Analysis of Digital Transformation in the History and Future of Modern Ports

open access: yesHawaii International Conference on System Sciences, 2017
Digital transformation is of utmost importance in the business world with major impacts on any of its sectors. Here we consider ports and logistics within maritime shipping to exemplify those developments.
Leonard Heilig, Silvia Schwarze, S. Voss
semanticscholar   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

A Modern History of Fiscal Prudence and Profligacy

open access: yesSocial Science Research Network, 2013
We draw on a newly collected historical dataset of fiscal variables for a large panel of countries — to our knowledge, the most comprehensive database currently available — to gauge the degree of fiscal prudence or profligacy for each country over the ...
P. Mauro   +3 more
semanticscholar   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Disturbing Attachments: Genet, Modern Pederasty, and Queer History

open access: yes, 2017
Jean Genet (1910–1986) resonates, perhaps more than any other canonical queer figure from the pre-Stonewall past, with contemporary queer sensibilities attuned to a defiant non-normativity.
Kadji Amin
semanticscholar   +1 more source

A review of ASA physical status – historical perspectives and modern developments

open access: yesAnaesthesia, 2019
The American Society of Anesthesiologists (ASA) physical status is a tool commonly used to classify a patient's physical fitness before surgery. Since its introduction in 1941 it has undergone very few modifications to improve its reliability and to ...
D. Mayhew, V. Mendonca, B. Murthy
semanticscholar   +1 more source

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