Results 71 to 80 of about 749,333 (289)
Advanced Science, EarlyView.This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia +5 more
wiley +1 more source
Domestic UK retrofit challenge: Barriers, incentives and current performance leading into the green deal [PDF]
, 2012 Copyright @ 2012 Elsevier - The official published version can be accessed from the link below.This paper reviews the thermal performance of the existing UK housing stock, the main fabric efficiency incentive schemes and the barriers to obtaining deep ...
Dowson, M +3 more
core +1 more source
Advanced Science, EarlyView.Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka +3 more
wiley +1 more source
Localized NF‐κB Inhibition Reduces Lipid Nanoparticle‐Associated Inflammation
Advanced Science, EarlyView.Lipid nanoparticles (LNPs) activate NF‐κB and provoke inflammation that limits therapeutic delivery. By encapsulating selective NF‐κB inhibitors within LNPs, localized suppression of inflammatory signaling is achieved without compromising mRNA expression.
Carolann L. Espy +16 more
wiley +1 more source
Advanced Science, EarlyView.Long‐Tea‐CLIP (Contrastive Language‐Image Pre‐training) presents a multimodal AI framework that integrates visual, metabolomic, and sensory knowledge to grade green tea across appearance, soup color, aroma, taste, and infused leaf. By combining expert‐guided modeling with CLIP‐supervised learning, the system delivers fine‐grained quality evaluation and
Yanqun Xu +9 more
wiley +1 more source
SOME SPECIFIC FEATURES OF ENERGY CONSUMPTION IN MODERN RESIDENTIAL BUILDINGS
Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2018 Over the past 20 years there have been significant changes in the customer requirements for housing in the countries of the former USSR. Besides, new materials and construction products, such as the ones for sealed windows and balcony doors have appeared
S. N. Osipov +2 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang +9 more
wiley +1 more source
Art: Tate Modern — The Switch House [PDF]
British Journal of General Practice, 2016 Tate Modern opened in grubby Southwark in 2001. I was there, a cub deputy editor at the BJGP . To general astonishment, Nick Serota (now Sir but still insistently Nick), director of the Tate Gallery, had chosen a grand but derelict power station, designed by Giles Gilbert Scott in the 1950s, as a home for the Tate’s collection of modern art, mainly ...
openaire +2 more sources
Advanced Science, EarlyView.This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong +7 more
wiley +1 more source
Social Security Policy and Vindictiveness [PDF]
This paper uses the work of Jock Young (2002, 2003) on the emergence of vindictiveness in late modern society to examine two recent developments – the withdrawal, in certain circumstances, of Housing Benefit from those people evicted for \'anti-social ...
Chris Grover
core