Results 91 to 100 of about 749,333 (289)

Cryoablation Activates the cGAS–STING‐CXCL10 Axis in Macrophages to Enhance Anti‐Tumor Immunity in NSCLC

open access: yesAdvanced Science, EarlyView.
Tumor dsDNA released by cryoablation is taken up by macrophages, activating the cGAS‐STING signaling pathway. This leads to an expansion of the CXCL10+ macrophage pool and increased secretion of CXCL10, which in turn recruits CXCR3+ T cells from draining lymph nodes into the tumor microenvironment to exert anti‐tumor effects.
Xinxin Zhi   +17 more
wiley   +1 more source

Modern Housing, Regionalism and Mediterraneanism in Cyprus (1930–1974)

open access: yesBuildings
This study examines the transformation of modern residential architecture in Cyprus between 1930 and 1974 through 14 representative residences selected across four historical periods.
Cemile Çakmak Aydınlı   +1 more
doaj   +1 more source

Housing finance in transition economies : the early years in Eastern Europe and the former Soviet Union [PDF]

open access: yes
The transition to markets dominates the development agenda of the 1990s. Financial sector reforms are central to a successful transition to a market economy.
Renaud, Bertrand M.
core  

CTBPro: A Next‐Generation Cholera Toxin Subunit B‐Based Neuroanatomical Tracer With Superior Brightness, Stability, and Sensitivity for Enhanced Neural Circuit Mapping

open access: yesAdvanced Science, EarlyView.
CTBPro is a next‐generation cholera toxin B–based tracer engineered by fusing CTB to the ultra‐stable fluorescent protein mBaojin. Exhibiting markedly enhanced molar brightness, CTBPro enables high‐fidelity neuronal labeling across multiple administration routes.
Xinghua Quan   +12 more
wiley   +1 more source

The Evolution of Exchange [PDF]

open access: yes
The aim of the paper is to introduce the modern techniques of evolutionary game theory introduced into economics by Young (1993) and others to analyze exchange economies.
Oscar Volij
core  

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

open access: yesAdvanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo   +19 more
wiley   +1 more source

Laparoscopic Delivery of a MnO2‐P‐ICG Patch for Photodynamic Therapy and NK Cell‐Driven Immunotherapy in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin   +14 more
wiley   +1 more source

Modernity and Housing

open access: yesTaḥqīqāt-i Farhangī-i Īrān, 2008
This article analyzes rural housing from a cultural point of view in the past and present. It studies housing as one of the main elements of lifestyle to understand the rural life as a whole. The author, first, studies the effects of modernity on housing culture in the areas such as modernization, rationalization, secularisation, globalization ...
openaire   +1 more source

Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy

open access: yesAdvanced Science, EarlyView.
Mechanical unloading suppresses bone Piezo1 expression, which reduces circulating undercarboxylated osteocalcin (unOCN). unOCN reduction subsequently exacerbates IMM‐induced Fndc5/Irisin decrease and drives severe muscle atrophy. Bone Piezo1 activation or exogenous osteocalcin/Irisin ameliorate muscle atrophy, while muscle‐specific Gprc6a or Fndc5 ...
Zhaolu Wang   +5 more
wiley   +1 more source

Spatial Impact of New Housing Trends in the Periphery of Istanbul Metropolitan Area [PDF]

open access: yes
Globalization had a significant effect on socio-economic and spatial changes in Istanbul as the largest city of Turkey following the trends in other cities of the world since the beginning of 1980. In this transformation process which the city center was
Ferhan Gezici, Tuba Inal Cekic
core  

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