Results 171 to 180 of about 74,543,651 (311)

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

Advanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao, Yuqing Song, Fang Yang, Menghui Guo, Libin Jiang, Xiaoyue Quan, Wei Wei, Xinyang Wang, Tianshu Han, Mingyuan Liu, Wenbo Jiang   +10 more
wiley   +1 more source

Library Line, June, 1970

, 2018
The County Line was a public, informational publication of the Toledo Lucas County Public Library. The first issue came out in March 1970, and it continued until December 1992.
Toledo Lucas County Public Library
core  

Computationally Evidence‐Grounded Sequence‐First Design of Peptide Binders

Advanced Science, EarlyView.
BOND‐PEP enables controllable, sequence‐first peptide binder design by grounding generation in binding evidence retrieved for each target. It uses topology‐conditioned message passing to integrate relevant peptide examples with the target protein sequence, forming a residue‐level representation that guides the generation of diverse, target‐specific ...
Wenze Ding
wiley   +1 more source

Book-embedded hair reveals mineral-rich diets among urban commoners in early modern to modern Japan. [PDF]

Sci Rep
Maruyama A, Kuwaki S, Kimura S, Sanada Y, Oikawa M, Futatsukawa S, Kohmatsu Y, Iriguchi A.   +7 more
europepmc   +1 more source

Library Line, Winter 1999

, 2018
The Library Line was a publication of the Toledo Lucas County Public Library that ran from 1993 through 2010. It covered library news, events, readers' advisory, and listed donors. This edition is undated, but appears to have been published in the winter
Toledo Lucas County Public Library
core  

Multi‐Omics Integration Identifies a CDH3‐Associated Malignant Epithelial State and Immunosuppressive Niche to Predict Prognosis in Thymic Epithelial Tumors

Advanced Science, EarlyView.
Single‐cell, spatial, molecular, and pathology analyses identify a CDH3‐associated malignant epithelial state in thymic epithelial tumors. This state links stem‐like and EMT programs to M2 macrophage–rich immunosuppressive niches, genomic instability, poor survival, and drug vulnerability.
Yuntao Feng, Jingyu Chen, Lang Xia, Tao Wang, Yuzhou Wang, Lei Zhang, Guofang Zhao, Long Xu, Juemin Yu, Yunlang She, Junqi Wu, Yue Zhao, Chang Chen, Deping Zhao   +13 more
wiley   +1 more source

A journal that grows older and stays young. [PDF]

J Bacteriol
Dong T.
europepmc   +1 more source

WHAT AFFECTS SATISFACTION LABOR OF MODERN LIBRARY WORKER? (BASED ON RESEARCH) [PDF]

Vestnik Tomskogo gosudarstvennogo universiteta. Kul'turologiya i iskusstvovedenie, 2015
openaire   +1 more source

Deep Learning‐Driven Discovery and Engineering of an Efficient PETase for Depolymerization and Detoxification of PET Microplastics Under Physiological Conditions

Advanced Science, EarlyView.
A deep learning–driven pipeline mining 246 million protein sequences uncovers AhPETase, an evolutionarily distinct PET hydrolase. Engineered variant AhPETaseM1 degrades post‐consumer PET microplastics under physiological conditions and reverses microplasticinduced cytotoxicity in human lung and colon cells, establishing enzymatic microplastic ...
Yuxuan Wang, Shijie He, Yuheng Chang, Sheng Mao, Jianan Canal Li, Binbin Chen, Hongxun Gao, Mingchun Xu, Chenxu Liu, Yajie Wang   +9 more
wiley   +1 more source

De novo assembly and authentication of ancient DNA metagenomes with nf-core/mag. [PDF]

PLoS Comput Biol
Fellows Yates JA, Hübner A, Borry M, nf-core community, Warinner C.   +4 more
europepmc   +1 more source