Results 161 to 170 of about 1,411,743 (318)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

High-frequency EEG synchronization modes as a stable biometric signature in humans. [PDF]

iScience
Vaezi H, Hossein-Zadeh GA.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Innovation modes and productivity in the UK

, 2008
This paper is motivated by the aim to develop appropriate indicators capturing modes of innovation by UK enterprises, examine how such innovation practices vary across regions and industries and explore the extent to which they have an impact on ...
Frenz, Marion, Lambert, Ray
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Regulatory mechanisms of two epiphytic cultivation modes of Cunninghamia lanceolata on growth, disease resistance and root-stem characteristics of Dendrobium devonianum. [PDF]

BMC Plant Biol
Sun C, Han Q, He X, Van Sam H, Fu W, Tang J, Zhang N.   +6 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

An Inquiry into Modes of Existence

, 2012
site webPlateforme d’enquête collective sur les modes d’existences développée pour l’ERC AIME de Bruno ...
Latour, Bruno, Girard, Paul, Jacomy, Alexis, Guido, Daniele, Plique, Guillaume, Leclercq, Christophe, Ricci, Donato, Jullian de La Fuente, Pierre   +7 more
core  

The Effects of Different Culture Modes on the Nutritional Quality of <i>Procambarus clarkii</i> and Mechanistic Insights: A Metabolomic Perspective. [PDF]

Biology (Basel)
Liu T, Tian J, Zhang L, Chen J, Yu Y, Tian C, Gan J.   +6 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

OPTICAL PHONON MODES IN QUANTUM WIRES

, 1992
Based on numerical results, the characteristics of each type of optical phonon mode in one-dimensional (1D) quantum wires are illustrated. The analytical formulae for 1D bulk-like optical displacements and associated electrostatic potentials are ...
ZHU BF CHINESE ACAD SCIINST SEMICONDNATL LAB SUPERLATTICES & MICROSTRUCTPOB 912BEIJING 100083PEOPLES R CHINA, ZHU BF   +1 more
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