Results 221 to 230 of about 6,177,010 (327)

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

MeRIP-Seq initially revealed the role of m6A modification in Chinese sacbrood virus-infected <i>Apis cerana</i> larvae. [PDF]

Front Microbiol
Liu Y, Bai H, Qiu H, Fei D, Ma M.
europepmc   +1 more source

Eine Modification des Liebig'schen Kühlapparates [PDF]

, 1895
J. J. L. van Rijn
openalex   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Circuit logic: interdependent RNA modifications shape mRNA and noncoding RNA structure and function. [PDF]

RNA
Porat J.
europepmc   +1 more source

Eine Modification des Zulkowsky'schen Apparates zur volumetrischen Bestimmung des Stickstoffes [PDF]

, 1880
E. Ludwig
openalex   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Research progress on N6-methyladenosine and non-coding RNA in multiple myeloma. [PDF]

Discov Oncol
Sun X, Zhou Y, Zhu W, Chen H.
europepmc   +1 more source

On Diseases of the Eye, their Modifications from Climate, etc., as Observed in India [PDF]

Wiesner Martin
openalex   +1 more source

ON THE MODIFICATION OF THE EXCITANT FOR LEUCOCYTES COMPOSED OF METHYLENE BLUE AND ATROPINE [PDF]

, 1909
H.C. Ross
openalex   +1 more source