Results 281 to 290 of about 4,784,459 (323)

The Role of Hydroxyl Modification of Peptidoglycan to Reduce the TTX Toxicity via Superior Absorption. [PDF]

Foods
Wang C, Guo Y, Zhang L, Miao J, Lu Y.
europepmc   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Histone modification changes upon exposure of human lung adenocarcinoma cells to nanoparticles. [PDF]

Sci Rep
Zhao X, Zhao L, Lin H, Wang X.
europepmc   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Identification of molecular subtypes based on pseudouridine modification in hepatocellular carcinoma. [PDF]

Cancer Cell Int
Xu W, Nie C, Liu Z, Liu Y, Yu P, Lv H, Chen B, Wang J, Wang S, Zhao J, He Y, Gao S, Chen X.   +12 more
europepmc   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Surface modification of polyetheretherketone for boosted osseointegration: A review. [PDF]

Biomater Transl
Chen Y, Chen Z, Lei K, Ding J, Yu L.
europepmc   +1 more source

Leucine-rich pentatricopeptide repeat-containing protein (LRPPRC)-stabilized lncRNA small nucleolar RNA host gene 15 (Snhg15) modulates hematopoietic injury induced by γ-ray irradiation via m⁶A modification. [PDF]

Mol Biomed
Zhang S, Cheng Y, Gao Y, Xu F, Wang Y, Zhang J, Shang Y, Li D, Fan S.   +8 more
europepmc   +1 more source

N⁶-methyladenosine and intervertebral disc degeneration: Advances in detection and pathological insights. [PDF]

J Orthop Translat
Liu B, Song G, Wang Y, Song C, Cao Y, Tong J, Wang Y, Fan X, Shi N, Zhao H, Fan D.   +10 more
europepmc   +1 more source