Results 51 to 60 of about 6,177,010 (327)
Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally
Nature, 2019 DNA and histone modifications have notable effects on gene expression1. Being the most prevalent internal modification in mRNA, the N6-methyladenosine (m6A) mRNA modification is as an important post-transcriptional mechanism of gene regulation2–4 and has
Huilin Huang +41 more
semanticscholar +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Characteristics of Winter Clouds and Precipitation over the Mountains of Northern Beijing
Advances in Meteorology, 2017 There are few studies which reported the characteristics of winter clouds and precipitation in the Haituo Mountains of Northern Beijing where the 2022 Winter Olympic Games will be held.
Xincheng Ma +4 more
doaj +1 more source
应用气象学报, 2022 observation is an important mean to obtain cloud physical information, which is important for weather modification research and operation. In China, aircraft observation research on cloud microphysical characteristics is mainly carried out in the ...
Liu Chunwen +4 more
doaj +1 more source
mRNA modifications in cardiovascular biology and disease: with a focus on m6A modification.
Cardiovascular Research, 2021 Among several known RNA modifications, N6-methyladenosine (m6A) is the most studied RNA epitranscriptomic modification and controls multiple cellular functions during development, differentiation, and disease.
Rajesh Kumari +6 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
暴雨灾害, 2022 Using observation data from a Ka-band millimeter wave cloud radar, a raindrop spectrometer, a L-band Basin in autumn is analyzed, especially focusing on its macro and microstructure characteristics and raindrop spectrum distribution characteristics.
Sirui FAN, Weijia WANG
doaj +1 more source
Modification, Test and Evaluation of Manually Operated Drum Type Seeder for Lowland Paddy [PDF]
, 1999 An experiment was conducted to improve the performance of the drum type seeder developed by the International Rice Research Institute for low land paddy. The machine was evaluated and compared with the conventional hand seeding method.
Ahmad, Desa, Islam, Md. Syedul
core
Synthesis of monodispersed Ag-doped bioactive glass nanoparticles via surface modification [PDF]
, 2016 © 2016 by the authors.Monodispersed spherical Ag-doped bioactive glass nanoparticles (Ag-BGNs) were synthesized by a modified Stöber method combined with surface modification.
Boccaccini, AR +5 more
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source