Results 131 to 140 of about 948,465 (312)

Thread Modification Method for Load Balance on Planetary Roller Screw Mechanism

open access: yes, 2018
Based on the relationship between the load distribution and the load deformation of the thread of the planetary roller screw mechanism (PRSM), a modification method of the roller thread is proposed.

core   +1 more source

Wettability characteristics modification of a magnesia partially stabilized zirconia using laser treatment and fundamental mechanism analysis

open access: yes, 2010
Wettability characteristics modification of a magnesia partially stabilized zirconia using laser treatment and fundamental mechanism ...
Jonathan Lawrence (7125611)   +1 more
core   +1 more source

N6-methyladenosine modification in ischemic stroke: Functions, regulation, and therapeutic potential

open access: yesHeliyon
N6-methyladenosine (m6A) modification is the most frequently occurring internal modification in eukaryotic RNAs. By modulating various aspects of the RNA life cycle, it has been implicated in a wide range of pathological and physiological processes ...
Fei Han
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Sodium metabisulfite as a contact allergen - An example of a rare chemical mechanism for protein modification

open access: yes, 2012
Background. Skin-sensitizing chemicals that cause allergic contact dermatitis do so by reacting with self-proteins such that the modified structure becomes antigenic.
Jonathan White   +11 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

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