Results 181 to 190 of about 2,075,261 (299)

Modification mechanism of Te and morphology evolution of primary Mg₂Si in an Al-20Mg₂Si alloy. [PDF]

Heliyon
Li C, Wang Z, Zhao Y, Du J, Ma Y, Li J, Sun F.   +6 more
europepmc   +1 more source

Study of the modification mechanism of heavy metal ions adsorbed by biomass-activated carbon doped with a solid nitrogen source. [PDF]

RSC Adv, 2019
Zheng W, Chen S, Liu H, Ma Y, Xu W.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Study on the Hydrophobic Modification Mechanism of Stearic Acid on the Surface of Coal Gasification Fly Ash. [PDF]

Molecules
Yang J, Li L, Wang W.
europepmc   +1 more source

A cytosine modification mechanism revealed by the structure of a ternary complex of deoxycytidylate hydroxymethylase from bacteriophage T4 with its cofactor and substrate. [PDF]

IUCrJ, 2019
Park SH, Suh SW, Song HK.
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Study of the Properties and Modification Mechanism of SBS-Modified Asphalt by Dry Process. [PDF]

Materials (Basel)
Wang Y, Guo S, Pei Z, Zhan S, Lin S, Ma K, Lei J, Yi J.   +7 more
europepmc   +1 more source

Nicotine Suppressed Fetal Adrenal StAR Expression via YY1 Mediated-Histone Deacetylation Modification Mechanism. [PDF]

Int J Mol Sci, 2016
Liu L, Wang JF, Fan J, Rao YS, Liu F, Yan YE, Wang H.   +6 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Evaluation of the Thermal Stability and Micro-Modification Mechanism of SBR/PP-Modified Asphalt. [PDF]

Polymers (Basel)
Zhang Q, Hou D, Li Z, Wang H, Dong S.
europepmc   +1 more source