Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Antikythera Mechanism PTMs brightened 01-05, small fragments 19-30 mostly inscribed
For inscription fragments (including offsets) side A is the side with text.These PTMs were constructed from images of all known remaining surfaces of the Antikythera Mechanism fragments housed in the National Archaeological Museum in Athens, Greece.
Antikythera Mechanism Research Project
core +17 more sources
Modification mechanism of silver nanoparticles-functionalized MW-CNT and GGBFS and CQDs on the structural properties of geopolymer reinforced-composite beam. [PDF]
Kırgız MS +9 more
europepmc +1 more source
Advances in the mechanisms of histone modification-mediated developmental toxicity induced by organophosphorus pesticides [PDF]
WU Mingmin +3 more
openalex +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Modified Bentonite As a Dissolve-Extrusion Composite and Its Modification Mechanism. [PDF]
Tan J +5 more
europepmc +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Rheological Properties and Modification Mechanism of Emulsified Asphalt Modified with Waterborne Epoxy/Polyurethan Composite. [PDF]
Li M, He Z, Yu J, Yu L, Shen Z, Kong L.
europepmc +1 more source

