Epileptic spasms in infants: can video-EEG reveal the disease’s etiology? A retrospective study and literature review [PDF]
Frontiers in Neurology, 2023 ObjectiveEpileptic spasms are a type of seizure defined as a sudden flexion or extension predominantly of axial and/or truncal limb muscles that occur with a noticeable periodicity. Routine electroencephalogram supports the diagnosis of epileptic spasms,
Raffaele Falsaperla +8 more
doaj +5 more sources
The Enigma of West Syndrome: A Case of Infantile Spasms Without Genetic Clues [PDF]
Case Reports in PediatricsWest syndrome is a distinctive type of epilepsy characterized by infantile spasms, hypsarrhythmia on EEG, and developmental regression. It affects children between 4 months and 2 years old, with an incidence of 2–3.5 per 10,000 births, being more common ...
Ali Raafat Ammar +4 more
doaj +3 more sources
Short-Term Changes in Hypsarrhythmia Assessed by Spectral Analysis: Group and Individual Assessments. [PDF]
Clin EEG NeurosciDATA AVAILABILITY STATEMENT : The data that support the findings of this study are available from the corresponding author, [JMF], upon reasonable request.Please read abstract in the article.https://journals.sagepub.com/home/EEGhj2024NeurologySDG-03 ...
Farinha JM +3 more
europepmc +4 more sources
West Syndrome in an Infant with Complete Corpus Callosal Agenesis
Archives of Medicine and Health Sciences, 2023 West syndrome is a severe form of epilepsy with onset in infancy and early childhood. The characteristic triad described includes infantile spasms (IS), an abnormal electroencephalogram (EEG) pattern referred to as hypsarrhythmia, and developmental ...
S. Sheetal +3 more
doaj +2 more sources
Micromachines, 2020 Epilepsy is a common neurological disorder. There is still a lack of methods to accurately detect cortical activity and locate lesions. In this work, a flexible electrocorticography (ECoG) electrode array based on polydimethylsiloxane (PDMS)-parylene was
Xinrong Li +12 more
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Mean global field power is reduced in infantile epileptic spasms syndrome after response to vigabatrin [PDF]
Frontiers in NeurologyPurposeInfantile epileptic spasms syndrome (IESS) is associated with abnormal neuronal networks during a critical period of synaptogenesis and brain plasticity. Hypsarrhythmia is a visual EEG biomarker used to diagnose IESS, assess response to treatment,
Arjun Nair +4 more
doaj +2 more sources
Kleefstra syndrome and epilepsy
Русский журнал детской неврологии, 2020 Kleefstra syndrome is a rare autosomal dominant genetic disorder caused by haploinsufficiency of the EHMT1 (Euchromatic Histone MethylTransferase 1). Patients with Kleefstra syndrome have following most common symptoms: moderate or severe intellectual ...
R. G. Gamirova +3 more
doaj +2 more sources
De novo variants in MAST4 related to neurodevelopmental disorders with developmental delay and infantile spasms: Genotype-phenotype association [PDF]
Frontiers in Molecular Neuroscience, 2023 ObjectiveThis study aims to prove that the de novo variants in MAST4 gene are associated with neurodevelopmental disorders (NDD) with developmental delay (DD) and infantile spasm (IS) and to determine the genotype-phenotype correlations.MethodsTrio-based
Xi Zhang +13 more
doaj +2 more sources
Эпилепсия и пароксизмальные состояния, 2017 West syndrome is an epileptic syndrome, characterized by a triad of symptoms: infantile spasms, hypsarrhythmia on interictal EEG, and a regression or delay of psycho-motoric development.
T. G. Okhapkina +5 more
doaj +2 more sources
A Multicenter Training and Interrater Reliability Study of the BASED Score for Infantile Epileptic Spasms Syndrome. [PDF]
J Clin NeurophysiolPURPOSE: The best possible outcomes in infantile epileptic spasms syndrome require electroclinical remission; however, determining electrographic remission is not straightforward.
Mytinger JR +36 more
europepmc +3 more sources