Results 11 to 20 of about 2,875,412 (170)

Biomimetic Deep Learning Networks With Applications to Epileptic Spasms and Seizure Prediction. [PDF]

IEEE Trans Biomed Eng
OBJECTIVE: In this study, we present a novel biomimetic deep learning network for epileptic spasms and seizure prediction and compare its performance with state-of-the-art conventional machine learning models.
Lucasius C, Grigorovsky V, Nariai H, Galanopoulou AS, Gursky J, Moshe SL, Bardakjian BL.   +6 more
europepmc   +3 more sources

Epileptic spasms relapse is associated with response latency but not conventional attributes of post-treatment EEG. [PDF]

Epilepsia Open
OBJECTIVE: Relapse of epileptic spasms after initial treatment of infantile epileptic spasms syndrome (IESS) is common. However, past studies of small cohorts have inconsistently linked relapse risk to etiology, treatment modality, and EEG features upon ...
Deckard E, Sathe R, Tabibzadeh D, Terango A, Groves A, Rajaraman RR, Nariai H, Hussain SA.   +7 more
europepmc   +3 more sources

Seminar in Epileptology: Normal awake and sleep patterns, interictal abnormalities, and ictal patterns on scalp EEG. [PDF]

Epileptic Disord
Abstract The accurate interpretation of scalp EEG remains an instrumental diagnostic component of epilepsy care. Knowledge of what constitutes normal EEG findings, non‐epileptiform abnormalities, and epileptiform patterns—both ictal and interictal—is essential for appropriate patient management.
Alcala-Zermeno JL, Katyal R, Frauscher B, Schomer D, Sperling MR, Strowd R, Tatum WO, Wirrell E, Beniczky S, Nascimento FA.   +9 more
europepmc   +2 more sources

Burst suppression pattern on EEG in West syndrome in an infant with heterozygous variant in the CACNA1A gene

Annals of Medical Science and Research, 2023
West syndrome is a severe epilepsy syndrome characterized by the classical triad of infantile spasms, hypsarrhythmia on electroencephalography (EEG) and psychomotor retardation.
Nikhil Gladson, Sheetal Sasikumar, Jiya Thankam Koshy   +2 more
doaj   +1 more source

Efficacy of Combined Therapy of ACTH plus Vigabatrin Compared to ACTH Alone for Treatment of Infantile Spasm-A RCT

Bangladesh Journal of Child Health, 2023
Background: Infantile spasms (epileptic spasm) is difficult to treat and has a high morbidity. So it’s crucial to initiate an early effective therapy. ACTH, Prednisolone and Vigabatrin have shown better efficacy on cessation of spasms.
Samsun Nahar Sumi, Banita Mistry, Md Ahsan Habib, M. Chandra, Seikh Azimul Hoque, N. Saha   +5 more
semanticscholar   +1 more source

Epileptic Spasms in CDKL5 Deficiency Disorder: Delayed Treatment and Poor Response to First-Line Therapies [PDF]

, 2023
OBJECTIVE: We aimed to assess the treatment response of infantile-onset epileptic spasms (ES) in CDKL5 deficiency disorder (CDD) vs other etiologies. METHODS: We evaluated patients with ES from the CDKL5 Centers of Excellence and the National Infantile ...
Benke, Timothy, Daniels, Carolyn, DeLeo, Michelle, Demarest, Scott, Greene, Caitlin, Harini, Chellamani, Haviland, Isabel, Katyayan, Akshat, Love-Nichols, Jamie, Marsh, Eric D, Moosa, Ahsan N, O\u27Connor Prange, Erin, Olson, Heather E, Pestana-Knight, Elia, Poduri, Annapurna, Pérez-Pérez, José R, Rajaraman, Rajsekar R, Suter, Bernhard, Swanson, Lindsay, Weisenberg, Judy, Zhang, Bo, Zhang, Xiaoming   +21 more
core   +2 more sources

West syndrome: a comprehensive review

Neurological Sciences, 2020
Since its first clinical description (on his son) by William James West (1793–1848) in 1841, and the definition of the classical triad of (1) infantile spasms; (2) hypsarrhythmia, and (3) developmental arrest or regression as “West syndrome”, new and ...
P. Pavone, A. Polizzi, S. Marino, G. Corsello, R. Falsaperla, S. Marino, M. Ruggieri   +6 more
semanticscholar   +1 more source

Cerebrospinal fluid corticotropin and cortisol are reduced in infantile spasms. [PDF]

, 1995
Infantile spasms respond to ACTH, and levels of the hormone in cerebrospinal fluid of untreated infants with this disorder were found to be lower than in age-matched controls. In this study we analyzed cerebrospinal fluid cortisol and ACTH using improved
Baram, TZ, Hanson, RA, Horton, EJ, Mitchell, WG, Snead, OC   +4 more
core   +2 more sources

Compound heterozygous mutations in UBA5 causing early-onset epileptic encephalopathy in two sisters. [PDF]

, 2017
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked FilesEpileptic encephalopathies are a group of childhood epilepsies that display high
Arnadottir, Gudny A, Arngrimsson, Reynir, Benonisdottir, Stefania, Gudbjartsson, Daniel F, Gudjonsson, Sigurjon A, Jensson, Brynjar O, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Kristjansson, Ragnar P, Magnusson, Olafur Th, Marelsson, Sigurdur E, Masson, Gisli, Oddsson, Asmundur, Saemundsdottir, Jona, Sigurdsson, Asgeir, Stefansson, Kari, Sulem, Gerald, Sulem, Patrick, Thorisson, Gudmundur A, Thorsteinsdottir, Unnur   +19 more
core   +1 more source

Hypsarrhythmia and spasms resolution after Valproic acid discontinuation in an infantile spasm patient

Neurosciences, 2019
Several studies have reported a variable benefit of valproic acid for the treatment of infantile spasm. However, valproic acid can also worsen spasms, as occurred with this child who presented with post-traumatic seizure which evolved to spasms.
Mohammed Alsallumi
semanticscholar   +1 more source