Results 201 to 210 of about 710,226 (268)

North Syracuse Central School District and North Syracuse Teaching Assistants and Licensed Practical Nurses Unit (2015) [PDF]

, 2015

core   +1 more source

DOT1L Drives Endothelial‐to‐Mesenchymal Transition and Fibrotic Vascular Remodeling via H3K79 Methylation

Advanced Science, EarlyView.
DOT1L as a central epigenetic regulator of EndoMT and pulmonary fibrosis. Acting as an early epigenetic switch, it translates TGFβ–SMAD signaling into H3K79me2‐mediated chromatin remodeling, selectively activates fibrosis‐related genes, and primes ECs for rapid mesenchymal transition.
Yaofeng Wang, Xing Peng, Jingjing Chen, Yun Zhang, Tinghong Zhang, Jingyuan Zhang, Jiaying Fan, Hui Zheng, Qiaoyuan Liu, Zhimin Song, Zhan‐Peng Huang, Shu Meng   +11 more
wiley   +1 more source

Standardization of In-Vitro Evaluation of Extracorporeal Life Support (ECLS) Devices for Research and Development. [PDF]

Interdiscip Cardiovasc Thorac Surg
Arens J, Belliato M, Broman LM, Clauser JC, Donker DW, Lorusso R, Malfertheiner M, Rajsic S, Swol J, Vercaemst L, Prahl Wittberg L, EACTS Innovation Committee, Section CPB , ECLS & MCS and the EuroELSO Innovation Group .   +13 more
europepmc   +1 more source

Real Estate Syndication [PDF]

, 1962

core   +1 more source

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

3D-guided high-degree posterior rotational osteotomy for avascular necrosis in pediatric femoral neck fractures: A three-case study. [PDF]

J Child Orthop
Watanabe M, Kagaya S, Kuzushima D, Kachi I.   +3 more
europepmc   +1 more source

George Junior Republic Union Free School District and George Junior Republic Teachers Organization (2004) [PDF]

, 2004

core   +1 more source

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

Advanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang, Zhaxi Zerang, Linjin You, Ziye Liu, Rong Nie, Fuwei Qi, Fenfen Gao, Chengmu Zhao, Wantong Ma, Jinghan He, Xiaoru Wang, Shanquan Wu, Bo Liu, Xinyao Liu, Dongsheng Lei, Dejuan Zhi, Dongsheng Wang   +16 more
wiley   +1 more source

Extra-articular Tenodesis for ACL Reconstruction: Who Needs it and is there a Superior Technique? [PDF]

Curr Rev Musculoskelet Med
Veizi E, Oliver-Welsh L, Koutserimpas C, Imat E, Getgood A.   +4 more
europepmc   +1 more source